Yixuan Shi, Yuzhe Zheng, Chengcong Huang, Shangyan Zhao, Xuan Li, Yuchen Lu, Yuzhi Wu, Peipei Li, Luning Wang, Yageng Li
{"title":"Influence of Processing Parameters on Additively Manufactured Architected Cellular Metals: Emphasis on Biomedical Applications.","authors":"Yixuan Shi, Yuzhe Zheng, Chengcong Huang, Shangyan Zhao, Xuan Li, Yuchen Lu, Yuzhi Wu, Peipei Li, Luning Wang, Yageng Li","doi":"10.3390/jfb16020053","DOIUrl":null,"url":null,"abstract":"<p><p>Laser powder bed fusion (LPBF) has emerged as a transformative additive manufacturing technique for fabricating architected cellular metallic structures, offering tailored properties for diverse biomedical applications. These structures are particularly well-suited for bone implants, scaffolds, and other load-bearing medical devices due to their ability to achieve lightweight designs, enhanced mechanical properties, and customized geometries. However, the complex interactions between LPBF process parameters and the resulting structural and mechanical properties pose significant challenges in achieving the precision and reliability required for clinical applications. This review provides a comprehensive analysis of the effects of LPBF process parameters, including laser power, scanning speed, and layer thickness, on key attributes such as dimensional accuracy, density, surface roughness, and microstructure. Their influence on the mechanical performance, including strength, fatigue resistance, and functional properties, is critically examined, with specific attention to biomedical relevance. The impact of lattice design factors, such as topology, unit cell size, and orientation, is also discussed, underscoring their role in optimizing biocompatibility and structural integrity for medical applications. Challenges such as surface defects, geometric inaccuracies, and microstructural inconsistencies are highlighted as key barriers to the broader adoption of LPBF in biomedical fields. Future perspectives focus on advancing LPBF technologies through process optimization and integration with advanced computational tools, such as machine learning, to enable efficient manufacturing of complex, patient-specific architectures. By addressing these challenges, LPBF has the potential to revolutionize the development of next-generation biomaterials, tailored to meet evolving clinical needs and improve patient outcomes.</p>","PeriodicalId":15767,"journal":{"name":"Journal of Functional Biomaterials","volume":"16 2","pages":""},"PeriodicalIF":5.0000,"publicationDate":"2025-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11856420/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Functional Biomaterials","FirstCategoryId":"5","ListUrlMain":"https://doi.org/10.3390/jfb16020053","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"ENGINEERING, BIOMEDICAL","Score":null,"Total":0}
引用次数: 0
Abstract
Laser powder bed fusion (LPBF) has emerged as a transformative additive manufacturing technique for fabricating architected cellular metallic structures, offering tailored properties for diverse biomedical applications. These structures are particularly well-suited for bone implants, scaffolds, and other load-bearing medical devices due to their ability to achieve lightweight designs, enhanced mechanical properties, and customized geometries. However, the complex interactions between LPBF process parameters and the resulting structural and mechanical properties pose significant challenges in achieving the precision and reliability required for clinical applications. This review provides a comprehensive analysis of the effects of LPBF process parameters, including laser power, scanning speed, and layer thickness, on key attributes such as dimensional accuracy, density, surface roughness, and microstructure. Their influence on the mechanical performance, including strength, fatigue resistance, and functional properties, is critically examined, with specific attention to biomedical relevance. The impact of lattice design factors, such as topology, unit cell size, and orientation, is also discussed, underscoring their role in optimizing biocompatibility and structural integrity for medical applications. Challenges such as surface defects, geometric inaccuracies, and microstructural inconsistencies are highlighted as key barriers to the broader adoption of LPBF in biomedical fields. Future perspectives focus on advancing LPBF technologies through process optimization and integration with advanced computational tools, such as machine learning, to enable efficient manufacturing of complex, patient-specific architectures. By addressing these challenges, LPBF has the potential to revolutionize the development of next-generation biomaterials, tailored to meet evolving clinical needs and improve patient outcomes.
期刊介绍:
Journal of Functional Biomaterials (JFB, ISSN 2079-4983) is an international and interdisciplinary scientific journal that publishes regular research papers (articles), reviews and short communications about applications of materials for biomedical use. JFB covers subjects from chemistry, pharmacy, biology, physics over to engineering. The journal focuses on the preparation, performance and use of functional biomaterials in biomedical devices and their behaviour in physiological environments. Our aim is to encourage scientists to publish their results in as much detail as possible. Therefore, there is no restriction on the length of the papers. The full experimental details must be provided so that the results can be reproduced. Several topical special issues will be published. Scope: adhesion, adsorption, biocompatibility, biohybrid materials, bio-inert materials, biomaterials, biomedical devices, biomimetic materials, bone repair, cardiovascular devices, ceramics, composite materials, dental implants, dental materials, drug delivery systems, functional biopolymers, glasses, hyper branched polymers, molecularly imprinted polymers (MIPs), nanomedicine, nanoparticles, nanotechnology, natural materials, self-assembly smart materials, stimuli responsive materials, surface modification, tissue devices, tissue engineering, tissue-derived materials, urological devices.