Fluoride Release from Two Commercially Available Dental Fluoride Gels-In Vitro Study.

IF 5 3区化学 Q1 POLYMER SCIENCE

Gels Pub Date : 2025-02-14 DOI:10.3390/gels11020135

Paweł J Piszko, Aleksandra Piszko, Sylwia Kiryk, Jan Kiryk, Julia Kensy, Mateusz Michalak, Jacek Matys, Maciej Dobrzyński

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Abstract

Fluoride has remained the most important ingredient in the prevention of tooth decay for many years. Therefore, fluoride prophylaxis should be highly individualized to provide patients with maximum benefits while minimizing the risk of toxic effects. This study aims to compare the degree of fluoride ion release from two commercially available dental fluoride gels (Fluormex and Fluor Protector Gel) in five different physiological solutions as well as their effect on pH. The concentration of fluoride ions and pH of tap water, distilled water, demineralized water, NaCl, and artificial saliva were evaluated before and after 48 h after dissolving and incubating the same amounts of gels. The concentration of fluoride ions was higher in solutions containing Fluormex than Fluor Pro-tector Gel (p < 0.05), with the highest concentration in demineralized water (16,917 ppm). It was accompanied by a decrease in pH below the critical value of 5.5 in all solutions except tap water. Not only the composition of the gel but also the chemical composition of the environment affects the release of fluoride ions. No relationship was found between the change in pH and the concentration of fluoride ions.

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两种市售氟牙凝胶的氟化物释放-体外研究

多年来，氟化物一直是预防蛀牙最重要的成分。因此，氟化物预防应高度个体化，为患者提供最大的利益，同时尽量减少毒性作用的风险。本研究旨在比较两种市售氟牙凝胶（Fluormex和Fluor Protector Gel）在五种不同生理溶液中氟离子的释放程度及其对pH的影响。在溶解和孵育相同量的凝胶48 h前和48 h后，评估自来水、蒸馏水、去离子水、NaCl和人工唾液的氟离子浓度和pH。氟离子浓度在含氟mex溶液中高于含氟Pro-tector Gel溶液（p < 0.05），其中除矿水中氟离子浓度最高（16,917 ppm）。除自来水外，所有溶液的pH值均低于临界值5.5。除凝胶的组成外，环境的化学成分也会影响氟化物离子的释放。pH值的变化与氟离子浓度没有关系。

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来源期刊

Gels POLYMER SCIENCE-

CiteScore

4.70

自引率

19.60%

发文量

707

审稿时长

11 weeks

期刊介绍： The journal Gels (ISSN 2310-2861) is an international, open access journal on physical (supramolecular) and chemical gel-based materials. Our aim is to encourage scientists to publish their experimental and theoretical results in as much detail as possible. Therefore, there is no restriction on the maximum length of the papers, and full experimental details must be provided so that the results can be reproduced. Short communications, full research papers and review papers are accepted formats for the preparation of the manuscripts. Gels aims to serve as a reference journal with a focus on gel materials for researchers working in both academia and industry. Therefore, papers demonstrating practical applications of these materials are particularly welcome. Occasionally, invited contributions (i.e., original research and review articles) on emerging issues and high-tech applications of gels are published as special issues.