Developing a core outcome set for nutrition care in adult outpatients with irritable bowel syndrome (COS-RD-IBS study)

IF 2.9 Q3 NUTRITION & DIETETICS

Clinical nutrition ESPEN Pub Date : 2025-02-22 DOI:10.1016/j.clnesp.2025.02.017

Sandra Jent , Joya Jelena Kristin Lüthi , André Meichtry , Natalie Sara Bez , Anita Bucher , Luzia Valentini , Gerhard Rogler

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引用次数: 0

Abstract

Background and aims

Irritable bowel syndrome (IBS) is a frequent disorder thought to be caused by a disturbance of the gut–brain axis. Nutrition interventions are an essential pillar of its treatment. However, there is no consensus on which outcomes should be applied to assess the effectiveness of nutrition care in IBS. Standardized outcome sets, or “core outcome sets“ (COS), have been proposed to harmonize outcomes in clinical research and practice. This project aims to develop a COS for dietitian-provided nutrition care in adults with IBS or food intolerances with intestinal symptoms, to be implemented in routine outpatient practice.

Methods

A comprehensive outcomes list was developed based on quantitative and qualitative studies, COS and guidelines on IBS, and important outcomes named by participants. Health service users, dietitians, gastroenterologists, and health care decision makers rated the outcomes in two Delphi survey rounds on their importance and ranked them in a third round. Data was analyzed by panel to account for the different views and sample sizes.

Results

A total of 192 participants registered for the Delphi process. The following 14 outcomes reached consensus in all panels after two rounds: perception of symptom triggering foods/nutrients, intake of trigger foods/nutrients, practicability of diet, adherence, digestive symptoms overall, abdominal pain, abdominal bloating, stool consistency, stool frequency, physical functioning related QoL, nutrition related QoL, social functioning related QoL, empowerment of self-care.

Conclusions

The Delphi process yielded in a 14 outcomes COS, which exceeds what is typically considered feasible in routine nutrition care. Further work is needed to refine the COS and to identify standardized measurement tools for each outcome.

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制定肠易激综合征成年门诊患者营养护理的核心结果集（COS-RD-IBS研究）。

背景和目的：肠易激综合征（IBS）是一种常见的疾病，被认为是由肠-脑轴紊乱引起的。营养干预是其治疗的重要支柱。然而，对于哪些结果应该用于评估肠易激综合征营养护理的有效性，目前还没有达成共识。标准化结果集，或“核心结果集”（COS），已被提出用于协调临床研究和实践的结果。该项目旨在为患有肠易激综合征或有肠道症状的食物不耐受的成人患者提供营养护理的COS，并在常规门诊实践中实施。方法：根据定量和定性研究、肠易激综合征（IBS）的COS和指南，以及参与者指定的重要结局，制定综合结局清单。卫生服务使用者、营养师、胃肠病学家和卫生保健决策者在两轮德尔菲调查中对结果的重要性进行评分，并在第三轮中进行排名。数据由小组分析，以说明不同的观点和样本量。结果：共有192名参与者报名参加德尔菲过程。两轮后，所有小组达成了以下14项结果的共识：对引发症状的食物/营养素的感知、引发食物/营养素的摄入、饮食的实用性、依从性、消化系统总体症状、腹痛、腹胀、大便一致性、大便频率、身体功能相关的生活质量、营养相关的生活质量、社会功能相关的生活质量、自我护理能力。结论：德尔菲过程产生了14个结果的COS，超过了常规营养护理通常认为可行的COS。需要进一步的工作来完善COS并为每项结果确定标准化的测量工具。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinical nutrition ESPEN NUTRITION & DIETETICS-

CiteScore

4.90

自引率

3.30%

发文量

512

期刊介绍： Clinical Nutrition ESPEN is an electronic-only journal and is an official publication of the European Society for Clinical Nutrition and Metabolism (ESPEN). Nutrition and nutritional care have gained wide clinical and scientific interest during the past decades. The increasing knowledge of metabolic disturbances and nutritional assessment in chronic and acute diseases has stimulated rapid advances in design, development and clinical application of nutritional support. The aims of ESPEN are to encourage the rapid diffusion of knowledge and its application in the field of clinical nutrition and metabolism. Published bimonthly, Clinical Nutrition ESPEN focuses on publishing articles on the relationship between nutrition and disease in the setting of basic science and clinical practice. Clinical Nutrition ESPEN is available to all members of ESPEN and to all subscribers of Clinical Nutrition.