Advances in Nasopharyngeal Carcinoma Staging: from the 7th to the 9th Edition of the TNM System and Future Outlook.

IF 4.7 2区医学 Q1 ONCOLOGY

Current Oncology Reports Pub Date : 2025-02-25 DOI:10.1007/s11912-025-01651-9

Binhao Wu, Xiaozhong Chen, Caineng Cao

{"title":"Advances in Nasopharyngeal Carcinoma Staging: from the 7th to the 9th Edition of the TNM System and Future Outlook.","authors":"Binhao Wu, Xiaozhong Chen, Caineng Cao","doi":"10.1007/s11912-025-01651-9","DOIUrl":null,"url":null,"abstract":"Purpose of review: Nasopharyngeal carcinoma (NPC), characterized by its aggressive nature and sensitivity to radiation, demands accurate staging for optimal clinical outcomes. The purpose of this review was to provides a comprehensive overview of the evolution of the TNM staging system for NPC based on recent and previously published studies, with particular emphasis on the transition from the 7th to the 9th edition.Recent findings: The 9th edition introduces critical changes, particularly in the N and M classifications, to enhance prognostic accuracy. Our analysis also incorporates the burgeoning roles of biomarkers, especially Epstein-Barr virus (EBV)-DNA, and the potential of Artificial Intelligence (AI) in refining NPC staging. Each iteration of the TNM staging system for NPC has successfully enhanced the prognostic precision of NPC, with notable advancements from the 7th to the 9th edition. We also delves into the incorporation of biomarkers, such as EBV-DNA, and the potential of AI in refining staging accuracy. These innovations are anticipated to offer personalized prognoses and inform tailored treatment strategies for NPC patients in the future.","PeriodicalId":10861,"journal":{"name":"Current Oncology Reports","volume":" ","pages":""},"PeriodicalIF":4.7000,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current Oncology Reports","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s11912-025-01651-9","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"ONCOLOGY","Score":null,"Total":0}

引用次数: 0

Abstract

Purpose of review: Nasopharyngeal carcinoma (NPC), characterized by its aggressive nature and sensitivity to radiation, demands accurate staging for optimal clinical outcomes. The purpose of this review was to provides a comprehensive overview of the evolution of the TNM staging system for NPC based on recent and previously published studies, with particular emphasis on the transition from the 7th to the 9th edition.

Recent findings: The 9th edition introduces critical changes, particularly in the N and M classifications, to enhance prognostic accuracy. Our analysis also incorporates the burgeoning roles of biomarkers, especially Epstein-Barr virus (EBV)-DNA, and the potential of Artificial Intelligence (AI) in refining NPC staging. Each iteration of the TNM staging system for NPC has successfully enhanced the prognostic precision of NPC, with notable advancements from the 7th to the 9th edition. We also delves into the incorporation of biomarkers, such as EBV-DNA, and the potential of AI in refining staging accuracy. These innovations are anticipated to offer personalized prognoses and inform tailored treatment strategies for NPC patients in the future.

查看原文本刊更多论文

求助全文

约1分钟内获得全文求助全文

来源期刊

Current Oncology Reports ONCOLOGY-

CiteScore

8.50

自引率

0.00%

发文量

187

审稿时长

6-12 weeks

期刊介绍： This journal aims to review the most important, recently published clinical findings in the field of oncology. By providing clear, insightful, balanced contributions by international experts, the journal intends to serve all those involved in the care of those affected by cancer. We accomplish this aim by appointing international authorities to serve as Section Editors in key subject areas, such as cancer prevention, leukemia, melanoma, neuro-oncology, and palliative medicine. Section Editors, in turn, select topics for which leading experts contribute comprehensive review articles that emphasize new developments and recently published papers of major importance, highlighted by annotated reference lists. An international Editorial Board reviews the annual table of contents, suggests articles of special interest to their country/region, and ensures that topics are current and include emerging research. Commentaries from well-known figures in the field are also provided.