Avocado Oil: Recent Advances in Its Anti-diabetic Potential.

IF 1.5 4区医学 Q3 MEDICINE, RESEARCH & EXPERIMENTAL

Current Medical Science Pub Date : 2025-02-01 Epub Date: 2025-02-25 DOI:10.1007/s11596-025-00010-w

Dorji Drakpa, Taniya Paul, Sukriti Chakrabarty, Karma Jigdrel, Prasun Mukherjee, Jeena Gupta

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引用次数: 0

Abstract

Background: Diet plays a crucial role in insulin resistance and diabetes, with high-fat and high-carbohydrate diets being major contributors. However, the type of fat consumed is critical, as different fatty acids impact insulin sensitivity differently.

Objective: This review examines the potential benefits of avocado oil, which is rich in monounsaturated fatty acids (MUFAs), in improving glycaemic control and lipid metabolism. It also explores variations in avocado oil composition across different avocado cultivars.

Methods: Experimental and clinical studies were analysed to assess the metabolic effects of avocado oil. The impact of MUFAs on insulin sensitivity, lipid profiles, and metabolic health was reviewed, alongside the influence of fruit quality, maturity, and cultivar differences.

Results: Avocado oil may enhance glycaemic control and lipid metabolism, benefiting individuals with diabetes and hypercholesterolemia. However, its composition varies significantly across avocado variants such as Hass, Reed, Ettinger, and Fuerte, influencing its therapeutic properties.

Conclusion: Avocado oil's high MUFA content offers promising metabolic benefits. Further research is needed to standardize its therapeutic application, considering cultivar-dependent variations in composition.

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牛油果油：其抗糖尿病潜力的最新进展。

背景：饮食在胰岛素抵抗和糖尿病中起着至关重要的作用，高脂肪和高碳水化合物饮食是主要因素。然而，摄入的脂肪类型是至关重要的，因为不同的脂肪酸对胰岛素敏感性的影响是不同的。目的：本文综述了鳄梨油在改善血糖控制和脂质代谢方面的潜在益处，鳄梨油富含单不饱和脂肪酸（MUFAs）。它还探讨了不同鳄梨品种的鳄梨油成分的变化。方法：分析实验和临床研究，以评估鳄梨油的代谢作用。本文综述了MUFAs对胰岛素敏感性、脂质谱和代谢健康的影响，以及果实品质、成熟度和品种差异的影响。结果：鳄梨油可以增强血糖控制和脂质代谢，对糖尿病和高胆固醇血症患者有益。然而，它的成分在不同的鳄梨品种之间有很大的差异，比如哈斯、里德、艾丁格和富尔特，这影响了它的治疗特性。结论：鳄梨油的高MUFA含量提供了有希望的代谢益处。考虑到其成分的品种依赖性变化，需要进一步的研究来规范其治疗应用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Current Medical Science Biochemistry, Genetics and Molecular Biology-Genetics

CiteScore

4.70

自引率

0.00%

发文量

126

期刊介绍： Current Medical Science provides a forum for peer-reviewed papers in the medical sciences, to promote academic exchange between Chinese researchers and doctors and their foreign counterparts. The journal covers the subjects of biomedicine such as physiology, biochemistry, molecular biology, pharmacology, pathology and pathophysiology, etc., and clinical research, such as surgery, internal medicine, obstetrics and gynecology, pediatrics and otorhinolaryngology etc. The articles appearing in Current Medical Science are mainly in English, with a very small number of its papers in German, to pay tribute to its German founder. This journal is the only medical periodical in Western languages sponsored by an educational institution located in the central part of China.