A Review of Hand Eczema Subtypes: Clinical Features, Biomarkers and Treatment Strategies

IF 4.8 1区 医学 Q2 ALLERGY
David Pesqué, Juan Francisco Silvestre-Salvador, Ana Carolina Figueiredo, Ramon Maria Pujol, Margarida Gonçalo, Ana María Giménez-Arnau
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引用次数: 0

Abstract

Hand eczema is a common dermatological condition that significantly impairs quality of life. The classification of hand eczema has been considered an essential step for its management. The diagnosis of hand eczema relies on the aetiological and clinical features of hand lesions, a process complicated by the heterogeneous presentations and the considerable overlap among its subtypes. However, the investigation of hand eczema biomarkers and the advent of targeted therapies have shed light on the underlying pathogenic mechanisms. This review adopts a subtype-specific approach to hand eczema, addressing clinical, pathogenic and therapeutic factors, with the aim of providing a comprehensive understanding of this heterogeneous condition from the perspective of its subtypes.

Abstract Image

手部湿疹亚型:临床特征、生物标志物和治疗策略综述
手部湿疹是一种常见的皮肤病,严重影响生活质量。手部湿疹的分类一直被认为是其管理的重要步骤。手部湿疹的诊断依赖于手部病变的病因学和临床特征,这一过程因其亚型的异质性和相当大的重叠而变得复杂。然而,手湿疹生物标志物的研究和靶向治疗的出现揭示了潜在的致病机制。本文对手部湿疹的亚型特异性研究进行综述,从临床、致病和治疗因素着手,以期从其亚型的角度对这种异质性疾病有一个全面的了解。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Contact Dermatitis
Contact Dermatitis 医学-过敏
CiteScore
4.60
自引率
30.90%
发文量
227
审稿时长
4-8 weeks
期刊介绍: Contact Dermatitis is designed primarily as a journal for clinicians who are interested in various aspects of environmental dermatitis. This includes both allergic and irritant (toxic) types of contact dermatitis, occupational (industrial) dermatitis and consumers" dermatitis from such products as cosmetics and toiletries. The journal aims at promoting and maintaining communication among dermatologists, industrial physicians, allergists and clinical immunologists, as well as chemists and research workers involved in industry and the production of consumer goods. Papers are invited on clinical observations, diagnosis and methods of investigation of patients, therapeutic measures, organisation and legislation relating to the control of occupational and consumers".
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