Bioresorbable Materials for Wound Management.

IF 3.4 3区 医学 Q1 ENGINEERING, MULTIDISCIPLINARY
Hye-Min Lee, Hanjun Ryu
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引用次数: 0

Abstract

Chronic wounds pose a significant healthcare challenge due to their risk of severe complications, necessitating effective management strategies. Bioresorbable materials have emerged as an innovative solution, offering advantages such as eliminating the need for secondary surgical removal, reducing infection risks, and enabling time-delayed drug delivery. This review examines recent advancements in bioresorbable wound healing materials, focusing on a systematic review of bioresorbable materials, systems incorporating electrical stimulation, and drug delivery technologies to accelerate tissue repair. The discussion encompasses the fundamental principles of bioresorbable materials, including their resorption mechanisms and key properties, alongside preclinical applications that demonstrate their practical potential. Critical challenges impeding widespread adoption are addressed, and prospects for integrating these cutting-edge systems into clinical practice are outlined. Together, these insights underscore the promise of bioresorbable materials in revolutionizing chronic wound care.

慢性伤口由于其严重并发症的风险,对医疗保健构成重大挑战,需要有效的管理策略。生物可吸收材料已成为一种创新的解决方案,其优点包括无需二次手术切除、降低感染风险和延迟给药。本文综述了生物可吸收伤口愈合材料的最新进展,重点对生物可吸收材料、电刺激系统和加速组织修复的药物输送技术进行了系统综述。讨论包括生物可吸收材料的基本原理,包括它们的吸收机制和关键特性,以及临床前应用,展示了它们的实际潜力。解决了阻碍广泛采用的关键挑战,并概述了将这些尖端系统整合到临床实践中的前景。总之,这些见解强调了生物可吸收材料在彻底改变慢性伤口护理方面的前景。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Biomimetics
Biomimetics Biochemistry, Genetics and Molecular Biology-Biotechnology
CiteScore
3.50
自引率
11.10%
发文量
189
审稿时长
11 weeks
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