Addressing Pain and Heavy Drinking among Patients in HIV-Care: A Pilot Study of an Integrated Telehealth Intervention

IF 2.7 2区 医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH
Tibor P. Palfai, Maya P. L. Kratzer, Jessica L. Taylor, John D. Otis, Michael R. Winter
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Abstract

Chronic pain is common among people living with HIV (PLWH) who engage in heavy drinking and both pain and heavy drinking influence quality of life, functioning, and HIV-outcomes. The purpose of this study was to: (1) test the acceptability and feasibility of a cognitive behavioral telehealth intervention (INTV) to reduce pain and heavy drinking among PLWH, (2) evaluate methods to implement a randomized controlled efficacy trial, and (3) provide preliminary information about its potential value. Forty-eight PLWH with chronic pain who engaged in heavy drinking were recruited from HIV-health clinics and social media. Following baseline assessment, participants were randomized to INTV or treatment-as-usual control (CTL). Participants completed outcome assessments at 3- and 6-months post-baseline. Results indicated that participants experienced high levels of satisfaction and showed strong intervention engagement. Over 85% of follow-up visits were completed across the two time-points. Condition comparisons showed small to moderate effects of the intervention on pain severity at 3-months (f2 = 0.05) but not at 6-months (f2 = 0.01). Effect sizes were consistent with less heavy episodic drinking for those in the INTV across timepoints (3-month aIRR = 0.72, 95% CI: [0.22, 2.41], 6-month aIRR = 0.71, 95% CI: [0.17, 2.96]) but only at 3-months for drinking quantity (3-month aIRR = 0.77, 95% CI: [0.29, 2.04]; 6-month aIRR = 1.00, 95% CI: [0.43, 2.29]). Results indicate that this is a feasible and acceptable approach for reducing chronic pain and heavy drinking among PLWH and that study methods may be useful for conducting a future efficacy trial. TRN: NCT03982433; Date of registration: 5/14/2019.

解决艾滋病毒护理患者的疼痛和酗酒:综合远程医疗干预的试点研究。
慢性疼痛在大量饮酒的艾滋病毒感染者(PLWH)中很常见,疼痛和大量饮酒都会影响生活质量、功能和艾滋病毒结局。本研究的目的是:(1)检验认知行为远程医疗干预(INTV)减轻PLWH患者疼痛和重度饮酒的可接受性和可行性;(2)评估实施随机对照疗效试验的方法;(3)提供其潜在价值的初步信息。研究人员从艾滋病毒健康诊所和社交媒体上招募了48名患有慢性疼痛、酗酒的PLWH患者。基线评估后,参与者被随机分为INTV组或常规治疗对照组(CTL)。参与者在基线后3个月和6个月完成结果评估。结果表明,参与者体验到高水平的满意度,并表现出强烈的干预参与。超过85%的随访是在两个时间点完成的。条件比较显示干预在3个月时对疼痛严重程度有小到中等的影响(f2 = 0.05),但在6个月时没有影响(f2 = 0.01)。INTV患者的效应大小与不同时间点的重度间歇性饮酒情况一致(3个月的aIRR = 0.72, 95% CI:[0.22, 2.41], 6个月的aIRR = 0.71, 95% CI:[0.17, 2.96]),但仅与3个月的饮酒量有关(3个月的aIRR = 0.77, 95% CI: [0.29, 2.04];6个月aIRR = 1.00, 95% CI:[0.43, 2.29])。结果表明,这是一种减少PLWH慢性疼痛和重度饮酒的可行和可接受的方法,该研究方法可能有助于开展未来的疗效试验。环境:NCT03982433;报名日期:2019年5月14日
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来源期刊
AIDS and Behavior
AIDS and Behavior Multiple-
CiteScore
6.60
自引率
13.60%
发文量
382
期刊介绍: AIDS and Behavior provides an international venue for the scientific exchange of research and scholarly work on the contributing factors, prevention, consequences, social impact, and response to HIV/AIDS. This bimonthly journal publishes original peer-reviewed papers that address all areas of AIDS behavioral research including: individual, contextual, social, economic and geographic factors that facilitate HIV transmission; interventions aimed to reduce HIV transmission risks at all levels and in all contexts; mental health aspects of HIV/AIDS; medical and behavioral consequences of HIV infection - including health-related quality of life, coping, treatment and treatment adherence; and the impact of HIV infection on adults children, families, communities and societies. The journal publishes original research articles, brief research reports, and critical literature reviews. provides an international venue for the scientific exchange of research and scholarly work on the contributing factors, prevention, consequences, social impact, and response to HIV/AIDS. This bimonthly journal publishes original peer-reviewed papers that address all areas of AIDS behavioral research including: individual, contextual, social, economic and geographic factors that facilitate HIV transmission; interventions aimed to reduce HIV transmission risks at all levels and in all contexts; mental health aspects of HIV/AIDS; medical and behavioral consequences of HIV infection - including health-related quality of life, coping, treatment and treatment adherence; and the impact of HIV infection on adults children, families, communities and societies. The journal publishes original research articles, brief research reports, and critical literature reviews.5 Year Impact Factor: 2.965 (2008) Section ''SOCIAL SCIENCES, BIOMEDICAL'': Rank 5 of 29 Section ''PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH'': Rank 9 of 76
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