Biochemical Activity of a Prototype of a Biological Preparation: Composite of Nanoparticles and Plant-Based Carbohydrates

IF 0.8 Q3 Engineering
G. I. Churilov, S. D. Polishchuk, D. G. Churilov, V. V. Churilova, A. V. Shemyakin
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引用次数: 0

Abstract

The toxicity of nanoparticles (NPs) and composites of metal NPs modified with polysaccharides is assessed by quantitative determination of the intracellular levels of reactive oxygen species (ROS). To create the nanocomposites, nanoparticles of copper with a size of 25–40 nm and a specific surface area of 30–60 m2/g; iron, 30–40 nm, 40–50 m2/g; cobalt 30–50 nm, 30–50 m2/g are used, and the polysaccharide of the medicinal plant knotweed is used as a natural polymer. The multifunctional nanobiocomposites possess synergistic properties of the natural polymer matrix and the material of the central nanoscale core. They have a prolonged effect and are less toxic than the NPs themselves. The developed nanocomposites can increase wheat yields by 10–40%, and when introduced into animal feed, increase their growth rates and reduce morbidity.

Abstract Image

一种生物制剂原型的生化活性:纳米颗粒和植物基碳水化合物的复合材料
通过定量测定细胞内活性氧(ROS)水平来评估纳米颗粒(NPs)和多糖修饰金属纳米颗粒复合材料的毒性。为了制造纳米复合材料,铜纳米粒子的尺寸为25-40纳米,比表面积为30-60 m2/g;铁,30-40 nm, 40-50 m2/g;采用钴30-50 nm, 30-50 m2/g,采用药用植物虎杖多糖作为天然聚合物。多功能纳米生物复合材料具有天然聚合物基体和中心纳米级核心材料的协同性能。它们具有持久的作用,而且毒性比NPs本身小。所开发的纳米复合材料可以使小麦产量提高10-40%,并且当引入动物饲料时,可以提高它们的生长速度并降低发病率。
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来源期刊
Nanotechnologies in Russia
Nanotechnologies in Russia NANOSCIENCE & NANOTECHNOLOGY-
CiteScore
1.20
自引率
0.00%
发文量
0
期刊介绍: Nanobiotechnology Reports publishes interdisciplinary research articles on fundamental aspects of the structure and properties of nanoscale objects and nanomaterials, polymeric and bioorganic molecules, and supramolecular and biohybrid complexes, as well as articles that discuss technologies for their preparation and processing, and practical implementation of products, devices, and nature-like systems based on them. The journal publishes original articles and reviews that meet the highest scientific quality standards in the following areas of science and technology studies: self-organizing structures and nanoassemblies; nanostructures, including nanotubes; functional and structural nanomaterials; polymeric, bioorganic, and hybrid nanomaterials; devices and products based on nanomaterials and nanotechnology; nanobiology and genetics, and omics technologies; nanobiomedicine and nanopharmaceutics; nanoelectronics and neuromorphic computing systems; neurocognitive systems and technologies; nanophotonics; natural science methods in a study of cultural heritage items; metrology, standardization, and monitoring in nanotechnology.
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