Adherence to HIV vertical transmission prevention (VTP) policies in a tertiary-level obstetric unit in South Africa.

IF 0.5 Q4 OBSTETRICS & GYNECOLOGY

Obstetric Medicine Pub Date : 2025-02-20 DOI:10.1177/1753495X251317263

Jarrod Zamparini, Sulaiman Hassan, Natasha Davies, Wilhelm Herbst, Shastra Bhoora, Robert Nyakoe, Lawrence Chauke

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引用次数: 0

Abstract

Background: HIV disproportionately affects women of childbearing age in South Africa. Despite progress in antiretroviral therapy access, challenges persist in HIV vertical transmission prevention (VTP).

Methods: We conducted a single-centre, retrospective observational audit of women delivering between May and August 2023 at the Charlotte Maxeke Johannesburg Academic Hospital in Johannesburg, South Africa to assess adherence to national VTP guidelines.

Results: Of 563 women, 22% (125/563) were living with HIV at their first antenatal visit, increasing to 24.3% (137/563) by delivery. HIV retesting rates declined from 46% (181/394) at the second visit to 20% (30/151) by the eighth. HIV viral load testing was performed in 71.5% of women (98/137) at delivery, with 72.4% (71/98) achieving viral suppression. Birth PCR testing was not performed for 21.1% (29/137) of HIV-exposed infants.

Conclusion: Significant gaps in HIV retesting, viral load monitoring, and birth PCR testing highlight ongoing challenges in VTP guideline adherence.

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在南非的一个三级产科单位坚持艾滋病毒垂直传播预防政策。

背景：艾滋病毒对南非育龄妇女的影响不成比例。尽管在获得抗逆转录病毒治疗方面取得了进展，但在艾滋病毒垂直传播预防（VTP）方面仍然存在挑战。方法：我们对2023年5月至8月在南非约翰内斯堡Charlotte Maxeke约翰内斯堡学术医院分娩的妇女进行了单中心、回顾性观察性审计，以评估对国家VTP指南的遵守情况。结果：563名妇女中，22%（125/563）在第一次产前检查时携带艾滋病毒，分娩时增加到24.3%（137/563）。艾滋病毒复检率从第二次访视时的46%（181/394）下降到第八次访视时的20%（30/151）。71.5%的妇女（98/137）在分娩时进行了HIV病毒载量检测，72.4%（71/98）的妇女实现了病毒抑制。21.1%（29/137）的hiv暴露婴儿未进行出生PCR检测。结论：HIV重新检测、病毒载量监测和出生PCR检测方面的显著差距凸显了VTP指南遵守方面的持续挑战。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Obstetric Medicine OBSTETRICS & GYNECOLOGY-

CiteScore

1.90

自引率

0.00%

发文量