A practical guide to dilating inflammatory bowel disease strictures.

IF 3.8 3区医学 Q2 GASTROENTEROLOGY & HEPATOLOGY

Expert Review of Gastroenterology & Hepatology Pub Date : 2025-04-01 Epub Date: 2025-03-03 DOI:10.1080/17474124.2025.2471873

Natasha K Klemm, Joseph D Feuerstein

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引用次数: 0

Abstract

Introduction: Stricturing Crohn's disease is a common phenotype and treatment aims to improve symptoms, prevent complications, assess for proximal bowel disease activity, and screen for upstream neoplasm. Management is challenging due to diagnostic limitations, stricture composition, and recurrence rate.

Areas covered: Categorizing a stricture as inflammatory or fibrotic is necessary to determine appropriate management. Inflammatory strictures are treated with medical therapy, and fibrostenotic strictures require endoscopic or surgical management. While EBD is increasingly utilized, stricture recurrence rates remain high, necessitating repeat endoscopic procedures or surgery. We performed a PubMed (MEDLINE database) search for the latest research on IBD-related stricture management, including detection, diagnosis, and medical and procedural therapies. We highlight the current literature on endoscopic techniques for the treatment of intestinal strictures and future areas of research.

Expert opinion: The field of intestinal stricture management is expected to evolve in the coming years and will include enhanced imaging modalities, medication optimization, and increasing use of advanced endoscopic techniques.

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导言：狭窄性克罗恩病是一种常见的表型，治疗的目的是改善症状、预防并发症、评估近端肠道疾病的活动性并筛查上游肿瘤。由于诊断的局限性、狭窄的构成和复发率，治疗具有挑战性：将狭窄分为炎症性狭窄和纤维性狭窄是确定适当治疗方法的必要条件。炎性狭窄可采用药物治疗，而纤维化狭窄则需要内窥镜或手术治疗。虽然 EBD 的应用越来越广泛，但狭窄复发率仍然很高，需要重复内窥镜手术或外科手术。我们在 PubMed（MEDLINE 数据库）上搜索了有关 IBD 相关狭窄治疗的最新研究，包括检测、诊断以及药物和手术疗法。我们重点介绍了目前有关内镜技术治疗肠狭窄的文献以及未来的研究领域：未来几年，肠狭窄治疗领域将不断发展，包括增强成像模式、优化药物治疗以及越来越多地使用先进的内窥镜技术。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Expert Review of Gastroenterology & Hepatology GASTROENTEROLOGY & HEPATOLOGY-

CiteScore

6.80

自引率

2.60%

发文量

审稿时长

6-12 weeks

期刊介绍： The enormous health and economic burden of gastrointestinal disease worldwide warrants a sharp focus on the etiology, epidemiology, prevention, diagnosis, treatment and development of new therapies. By the end of the last century we had seen enormous advances, both in technologies to visualize disease and in curative therapies in areas such as gastric ulcer, with the advent first of the H2-antagonists and then the proton pump inhibitors - clear examples of how advances in medicine can massively benefit the patient. Nevertheless, specialists face ongoing challenges from a wide array of diseases of diverse etiology.