The efficacy of notched music therapy vs conventional music therapy for chronic subjective tinnitus patients: a systematic review and meta-analysis.

IF 2.2 3区医学 Q2 OTORHINOLARYNGOLOGY

European Archives of Oto-Rhino-Laryngology Pub Date : 2025-07-01 Epub Date: 2025-02-24 DOI:10.1007/s00405-025-09260-9

Wen Jiang, Yun Zheng, Cheng Zheng, Rouxian Chen, Bin Li

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引用次数: 0

Abstract

Purpose: The etiology and mechanism of chronic subjective tinnitus (CST) are still unclear, thus there is no specific treatment yet. The notched music therapy (NMT) has been found to relieve patients' tinnitus symptoms, but its efficacy is still controversial. This study aims to resolve the controversy through meta pooling method.

Methods: By searching Embase, Pubmed, Elsevier, WOS, CNKI, and CBM (China Biology Medicine disc) databases, relevant literature on "notch music therapy" and "tinnitus" was obtained, and suitable clinical controlled trials were screened. Cochrane ROB v2.0 was used to assess the risk of literature bias, and the efficacy after treatment was evaluated by pooling the effect size of tinnitus handicap inventory (THI) and visual analog scale (VAS) between intervention group and control group.

Results: A total of 14 randomized controlled trial studies were included for quantitative analysis, with a total of 793 CST patients participating, including 395 patients in the intervention group and 398 patients in the control group. Among them, five studies were evaluated as biased with "some concerns of risk". The meta-analysis results showed a pooling effect size of THI score of patients after 3 months of treatment (MD = - 8.62, 95% CI (- 17.01, - 0.23), Z = - 2.01, P = 0.044) and VAS score of tinnitus after 3 months of treatment (MD = - 1.13, 95% CI (- 2.49, - 0.11), Z = - 2.14, P = 0.003) between NMT and conventional music therapy (CMT). Heterogeneity investigation and regression analysis found that notch frequency range, publication year, and patient age were not specific factors affecting the merged results. The sensitivity analysis results showed that the comprehensive effect size was stable and reliable, with no significant publication bias (P > 0.05).

Conclusion: Compared to traditional music therapy, notched music therapy can significantly reduce the scores of the tinnitus disability scale and tinnitus loudness score for patients after treatment. It is a good non-pharmacological treatment that is worthy of clinical promotion.

查看原文本刊更多论文

缺口音乐治疗与传统音乐治疗对慢性主观性耳鸣患者的疗效：一项系统回顾和荟萃分析。

目的：慢性主观性耳鸣（CST）的病因和发病机制尚不清楚，目前尚无专门的治疗方法。缺口音乐疗法（NMT）已被发现可以缓解患者的耳鸣症状，但其疗效仍存在争议。本研究旨在通过meta pooling方法解决争议。方法：通过检索Embase、Pubmed、Elsevier、WOS、CNKI、CBM（中国生物医学光盘）数据库，获取“notch music therapy”和“耳鸣”的相关文献，筛选合适的临床对照试验。采用Cochrane ROB v2.0评价文献偏倚风险，通过合并干预组与对照组耳鸣障碍量表（THI）和视觉模拟量表（VAS）的效应量评价治疗后的疗效。结果：共纳入14项随机对照试验研究进行定量分析，共纳入793例CST患者，其中干预组395例，对照组398例。其中，有5项研究被评估为“存在一定风险”。meta分析结果显示，NMT与传统音乐治疗（CMT）治疗3个月后患者THI评分（MD = - 8.62, 95% CI (- 17.01, - 0.23), Z = - 2.01, P = 0.044）和治疗3个月后耳鸣VAS评分（MD = - 1.13, 95% CI (- 2.49, - 0.11), Z = - 2.14, P = 0.003）存在池效应大小。异质性调查和回归分析发现，缺口频率范围、发表年份和患者年龄不是影响合并结果的特定因素。敏感性分析结果显示，综合效应量稳定可靠，无显著发表偏倚（P < 0.05）。结论：与传统音乐治疗相比，缺口音乐治疗可显著降低患者治疗后耳鸣失能评分和耳鸣响度评分。是一种很好的非药物治疗方法，值得临床推广。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

European Archives of Oto-Rhino-Laryngology 医学-耳鼻喉科学

CiteScore

5.30

自引率

7.70%

发文量

537

审稿时长

2-4 weeks

期刊介绍： Official Journal of European Union of Medical Specialists – ORL Section and Board Official Journal of Confederation of European Oto-Rhino-Laryngology Head and Neck Surgery "European Archives of Oto-Rhino-Laryngology" publishes original clinical reports and clinically relevant experimental studies, as well as short communications presenting new results of special interest. With peer review by a respected international editorial board and prompt English-language publication, the journal provides rapid dissemination of information by authors from around the world. This particular feature makes it the journal of choice for readers who want to be informed about the continuing state of the art concerning basic sciences and the diagnosis and management of diseases of the head and neck on an international level. European Archives of Oto-Rhino-Laryngology was founded in 1864 as "Archiv für Ohrenheilkunde" by A. von Tröltsch, A. Politzer and H. Schwartze.