Concomitant ATTR and AL Cardiac Amyloidosis With Matching 99m Tc-DPD Scintigraphy and 18 F-Flutemetamol PET/CT.

IF 9.6 3区医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Clinical Nuclear Medicine Pub Date : 2025-05-01 Epub Date: 2025-02-24 DOI:10.1097/RLU.0000000000005784

Joo Hyun O, Jong-Chan Youn, Eun Ji Han, Mi-Hyang Jung, Jung Yeon Lee, Sung-Soo Park, Yeoun Eun Sung, Chang-Ki Min

引用次数: 0

Abstract

Two distinct types of systemic amyloidosis-transthyretin (ATTR) and light chain (AL)-account for the majority of cardiac amyloidosis (CA), which have been considered mutually exclusive. Diagnostic confusion can arise when both proteins are identified from an amyloid deposit. We present a rare occurrence of histopathologically confirmed concomitant ATTR and AL CA captured on 99m Tc-3,3-diphosphono-1,2-propanodicarboxylic acid (DPD) scan and 18 F-flutemetamol (FMM) PET/CT.

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伴发ATTR和AL型心脏淀粉样变性伴99mTc-DPD显像和18f -氟替他莫PET/CT

两种不同类型的系统性淀粉样变性-转甲状腺素（ATTR）和轻链(AL)-占心脏淀粉样变性（CA）的大部分，它们被认为是相互排斥的。当两种蛋白都来自淀粉样蛋白沉积时，可能会出现诊断混淆。我们在99mtc -3,3-二膦-1,2-丙二甲酸（DPD）扫描和18f -氟替他莫（FMM） PET/CT上发现了罕见的组织病理学证实的合并ATTR和AL CA。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinical Nuclear Medicine 医学-核医学

CiteScore

2.90

自引率

31.10%

发文量

1113

审稿时长

2 months

期刊介绍： Clinical Nuclear Medicine is a comprehensive and current resource for professionals in the field of nuclear medicine. It caters to both generalists and specialists, offering valuable insights on how to effectively apply nuclear medicine techniques in various clinical scenarios. With a focus on timely dissemination of information, this journal covers the latest developments that impact all aspects of the specialty. Geared towards practitioners, Clinical Nuclear Medicine is the ultimate practice-oriented publication in the field of nuclear imaging. Its informative articles are complemented by numerous illustrations that demonstrate how physicians can seamlessly integrate the knowledge gained into their everyday practice.