Multifunctional nanoparticles for image-guided drug delivery in nuclear medicine: advancements and applications

IF 1.5 3区化学 Q3 CHEMISTRY, ANALYTICAL

Journal of Radioanalytical and Nuclear Chemistry Pub Date : 2025-01-06 DOI:10.1007/s10967-024-09960-2

Bilal AbdulMajeed Mukhlif, Muhammad Ikram Ullah, Subasini Uthirapathy, Soumya V. Menon, R. S. K. Sharma, Abed J. Kadhim, Swati Sharma, Bhanu Juneja, Munthar Kadhim Abosaoda, Wesam R. Kadhum

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Abstract

The advent of multifunctional nanoparticles has significantly transformed the landscape of image-guided drug delivery (IGDD) in nuclear medicine. This review presents a detailed examination of the progress and applications of these nanoparticles within the field. It discusses combining imaging techniques such as positron emission tomography (PET) and single-photon emission computed tomography (SPECT) with targeted drug delivery platforms, highlighting the nanoparticles’ ability to improve drug bioavailability and therapeutic outcomes. Additionally, the review addresses the challenges related to their translation into clinical practice. By analyzing recent studies and advancements, it seeks to provide insights into the potential of multifunctional nanoparticles for enhancing IGDD in nuclear medicine.

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来源期刊

Journal of Radioanalytical and Nuclear Chemistry 化学-分析化学

CiteScore

2.80

自引率

18.80%

发文量

504

审稿时长

2.2 months

期刊介绍： An international periodical publishing original papers, letters, review papers and short communications on nuclear chemistry. The subjects covered include: Nuclear chemistry, Radiochemistry, Radiation chemistry, Radiobiological chemistry, Environmental radiochemistry, Production and control of radioisotopes and labelled compounds, Nuclear power plant chemistry, Nuclear fuel chemistry, Radioanalytical chemistry, Radiation detection and measurement, Nuclear instrumentation and automation, etc.