Protocolo diagnóstico y terapéutico de la enfermedad ósea tumoral metastásica

Abstract

The bone is the most frequent site of solid tumor metastasis, which occur in up to 85% of prostate cancers and 40% of renal cancers. Complications (skeletal-related events —SER—) occur in approximately half of patients with bone metastases, representing an important source of comorbidities that affect not only quality of life, but also the survival of patients with cancer. The diagnosis is based on clinical suspicion and imaging tests, with biopsies reserved for select patients. Treatment is predominantly palliative, with the main objective being symptom relief (pain being the most common) and recovery of the patient's functionality through systemic (bisphosphonates and denosumab) and local (radiotherapy and surgery) treatment.