The effect of dill (Anethum graveolens) seeds on labor pain and progress: A systematic review and meta-analysis

IF 1.7 Q2 Medicine

Advances in integrative medicine Pub Date : 2024-09-24 DOI:10.1016/j.aimed.2024.09.003

Somayeh Makvandi , Leyla Karimi , Solmaz Mohammadi , Amir Vahedian-Azimi , Amirhossein Sahebkar

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引用次数: 0

Abstract

Background

In recent years, there has been growing interest in exploring the potential benefits of dill (Anethum graveolens) seeds in managing labor pain and promoting labor progress. This systematic review and meta-analysis aimed to gather and analyze all available evidence on the efficacy of dill seeds in reducing labor pain and facilitating labor progress.

Methods

The databases of PubMed/MEDLINE, Scopus, Cochrane Central Register of Controlled Trials (CENTRAL), and ScienceDirect have been searched since their inception until June 20, 2023. The risk of bias for clinical trials was evaluated using the Cochrane tool and the National Institutes of Health (NIH) quality assessment tool was used for the evaluation of cohort studies. Meta-analysis was performed on the extracted data. Heterogeneity was assessed using the Chi² and I² index. Meta-analyses of all the data were done using RevMan 5.4.

Results

A total of 341 studies were identified through the primary search and after data reduction, finally, five articles remained for assessment. The results showed that the duration of the first stage (MD = −1.71, 95 % CI −2.94--0.48, P = 0.006), second stage (MD = −9.90, 95 % CI −15.51--4.29, p = 0.0005), and third stage (MD = −1.34, 95 % CI −2.14--0.54, p = 0.001) of labor were statistically shorter in the dill seed group, compared with that in the control group. Also, regarding pain intensity during the active stage of labor, the results indicated a favorable outcome for dill seed both overall and in the subgroup analyses of cohort and RCT studies. However, the significant finding was present only in the cohort subgroup (p < 0.00001).

Conclusion

Using dill seeds in the active phase of labor in low-risk childbearing women could be an effective and low-cost intervention to reduce labor pain and accelerate labor progress. However, more high-quality clinical trials are needed to provide stronger scientific evidence.

查看原文本刊更多论文

背景近年来，人们对探索莳萝（Anethum graveolens）种子在控制分娩疼痛和促进分娩进展方面的潜在益处越来越感兴趣。本系统综述和荟萃分析旨在收集和分析有关莳萝籽在减轻分娩疼痛和促进分娩进展方面功效的所有可用证据。方法对 PubMed/MEDLINE、Scopus、Cochrane Central Register of Controlled Trials (CENTRAL) 和 ScienceDirect 等数据库进行了检索，检索时间从开始检索到 2023 年 6 月 20 日。临床试验的偏倚风险采用 Cochrane 工具进行评估，队列研究的评估采用美国国立卫生研究院（NIH）质量评估工具。对提取的数据进行了元分析。异质性采用 Chi2 和 I2 指数进行评估。使用 RevMan 5.4 对所有数据进行了 Meta 分析。结果通过初选搜索共找到 341 项研究，经过数据缩减后，最终剩下 5 篇文章进行评估。结果显示，与对照组相比，莳萝籽组第一产程（MD = -1.71, 95 % CI -2.94--0.48，P = 0.006）、第二产程（MD = -9.90, 95 % CI -15.51--4.29，P = 0.0005）和第三产程（MD = -1.34, 95 % CI -2.14--0.54，P = 0.001）的持续时间在统计学上更短。此外，关于分娩活跃期的疼痛强度，结果表明莳萝籽在总体上以及在队列研究和 RCT 研究的亚组分析中都有良好的效果。结论在低风险育龄妇女的分娩活跃期使用莳萝籽可能是一种有效且低成本的干预措施，可减轻分娩疼痛并加快产程。然而，还需要更多高质量的临床试验来提供更有力的科学证据。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Advances in integrative medicine INTEGRATIVE & COMPLEMENTARY MEDICINE-

CiteScore

3.20

自引率

11.80%

发文量

审稿时长

15 weeks

期刊介绍： Advances in Integrative Medicine (AIMED) is an international peer-reviewed, evidence-based research and review journal that is multi-disciplinary within the fields of Integrative and Complementary Medicine. The journal focuses on rigorous quantitative and qualitative research including systematic reviews, clinical trials and surveys, whilst also welcoming medical hypotheses and clinically-relevant articles and case studies disclosing practical learning tools for the consulting practitioner. By promoting research and practice excellence in the field, and cross collaboration between relevant practitioner groups and associations, the journal aims to advance the practice of IM, identify areas for future research, and improve patient health outcomes. International networking is encouraged through clinical innovation, the establishment of best practice and by providing opportunities for cooperation between organisations and communities.