A critical review on zinc oxide nanoparticles: Synthesis, properties and biomedical applications

Intelligent Pharmacy Pub Date : 2025-02-01 DOI:10.1016/j.ipha.2024.08.004

Suddhasattya Dey , Dibya lochan Mohanty , Noota Divya , Vasudha Bakshi , Anshuman Mohanty , Deepankar Rath , Sriparni Das , Arijit Mondal , Sourav Roy , Rajarshee Sabui

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Abstract

Background

ZnO-NPs is an inorganic metal oxide that meets as medicine, a preservative in packaging, as well as an antibacterial agent without risk. The qualities of ZnO-NPs are influenced by their size, shape, concentration, and length of contact with the bacterial cell. There are many uses for ZnO including food technology, agriculture, cosmetology, optoelectronics, drug transporters, and antibacterial agents.

Methods

The antibacterial potential of ZnO-NPs mediated by plant extracts is superior against bacterial and fungal infections and human diseases. Trifolium, Justicia adhathoda, Physalis alkekengi L, Cassia auriculata, Pretence blossoms, Aloe barbadenis, Pongamia pinnata, Limoniaacidissima, Plectranthusamboinicus, Sedum alfredii Hance, and Aspidoterys cordata have all been discovered as excellent sources for the synthesis of NPs. ZnO-NPs is an inorganic metal oxide that meets the above-mentioned requirements, which can be utilised as medicine, a preservative in packaging, as well as an antibacterial agent without risk16. The qualities of ZnO-NPs are influenced by their size, shape, concentration, and length of contact with the bacterial cell.

Conclusion

It provides an overview of the numerous synthesis approaches, characterization techniques, and biomedical uses of organically generated ZnO-NPs in food, pharmaceutical and textile sectors. It has been discovered that ZnO-NPs produced by green synthesis are more useful for pharmacological and biological applications, particularly antimicrobials.

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氧化锌纳米颗粒的合成、性能及生物医学应用综述

zno - nps是一种无机金属氧化物，可作为药品、包装防腐剂和抗菌剂使用，无风险。ZnO-NPs的质量受其大小、形状、浓度和与细菌细胞接触的长度的影响。氧化锌有许多用途，包括食品技术、农业、美容、光电子、药物转运和抗菌剂。方法植物提取物介导的ZnO-NPs对细菌、真菌感染和人类疾病具有较强的抑菌活性。已发现三叶草、江蓠、alkekengi L、木耳Cassia auriculata、伪善花、Aloe barbadenis、Pongamia pinnata、Limoniaacidissima、Plectranthusamboinicus、Sedum alfredii Hance和Aspidoterys cordata都是合成NPs的优良来源。ZnO-NPs是一种符合上述要求的无机金属氧化物，可作为药品、包装防腐剂和抗菌剂使用，且无风险16。ZnO-NPs的质量受其大小、形状、浓度和与细菌细胞接触的长度的影响。综述了有机合成ZnO-NPs的多种合成方法、表征技术以及在食品、制药和纺织等领域的生物医学应用。研究发现，绿色合成的ZnO-NPs在药理学和生物学，特别是抗菌剂方面具有更大的应用价值。

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Intelligent Pharmacy

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