A critical review on zinc oxide nanoparticles: Synthesis, properties and biomedical applications

Intelligent Pharmacy Pub Date : 2025-02-01 DOI:10.1016/j.ipha.2024.08.004

Suddhasattya Dey , Dibya lochan Mohanty , Noota Divya , Vasudha Bakshi , Anshuman Mohanty , Deepankar Rath , Sriparni Das , Arijit Mondal , Sourav Roy , Rajarshee Sabui

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Abstract

Background

ZnO-NPs is an inorganic metal oxide that meets as medicine, a preservative in packaging, as well as an antibacterial agent without risk. The qualities of ZnO-NPs are influenced by their size, shape, concentration, and length of contact with the bacterial cell. There are many uses for ZnO including food technology, agriculture, cosmetology, optoelectronics, drug transporters, and antibacterial agents.

Methods

The antibacterial potential of ZnO-NPs mediated by plant extracts is superior against bacterial and fungal infections and human diseases. Trifolium, Justicia adhathoda, Physalis alkekengi L, Cassia auriculata, Pretence blossoms, Aloe barbadenis, Pongamia pinnata, Limoniaacidissima, Plectranthusamboinicus, Sedum alfredii Hance, and Aspidoterys cordata have all been discovered as excellent sources for the synthesis of NPs. ZnO-NPs is an inorganic metal oxide that meets the above-mentioned requirements, which can be utilised as medicine, a preservative in packaging, as well as an antibacterial agent without risk16. The qualities of ZnO-NPs are influenced by their size, shape, concentration, and length of contact with the bacterial cell.

Conclusion

It provides an overview of the numerous synthesis approaches, characterization techniques, and biomedical uses of organically generated ZnO-NPs in food, pharmaceutical and textile sectors. It has been discovered that ZnO-NPs produced by green synthesis are more useful for pharmacological and biological applications, particularly antimicrobials.

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Intelligent Pharmacy

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