The effect of Nano-curcumin on migraine attacks: A systematic review and meta-analysis of randomized control trials

IF 1.7 Q2 Medicine

Advances in integrative medicine Pub Date : 2024-12-16 DOI:10.1016/j.aimed.2024.12.003

Reza Aletaha , Mahsa Kashtkar , Haleh Farshi , Maryam Cheraghi , Sarvin Sanaie , Nafiseh Ghassab-Abdollahi

{"title":"The effect of Nano-curcumin on migraine attacks: A systematic review and meta-analysis of randomized control trials","authors":"Reza Aletaha , Mahsa Kashtkar , Haleh Farshi , Maryam Cheraghi , Sarvin Sanaie , Nafiseh Ghassab-Abdollahi","doi":"10.1016/j.aimed.2024.12.003","DOIUrl":null,"url":null,"abstract":"<div><h3>Introduction</h3><div>The present study aimed to evaluate the effect of Nano-curcumin on the severity, frequency, and duration of migraine attacks among patients who suffer from this irritating headache.</div></div><div><h3>Methods</h3><div>PubMed, Scopus, Embase, Web of Science, ProQuest, The Cochrane Library, and google scholar were systematically searched up to December 30, 2022 in order to find the eligible studies investigating the effect of Nano-curcumin supplementation on the duration, severity, or frequency of migraine headache attacks. Only randomized controlled trials were included. RevMan (V 5.4) software was used to perform Meta-analysis and the results were reported using Mean difference with 95 % confidence intervals (CI).</div></div><div><h3>Results</h3><div>A total of three randomized controlled trials with participation of 126 patients were included. The result of Meta-analysis indicated that using Nano-curcumin supplementation significantly reduced the severity of migraine headache attacks in intervention group [-1.92; 95 % CI (-2.74, −1.09); p < 0.001]; But there was not significant difference in duration [-3.96; 95 % CI (-8.79, 0.89); p = 0.11], and frequency [-1.09; 95 % CI (-2.38, 0.19); p = 0.09] of migraine headache attacks between the intervention and control groups.</div></div><div><h3>Conclusions</h3><div>Nano-curcumin supplementation in patients suffering from migraine played an important role in reducing severity of migraine headache attacks compared to control group.</div></div>","PeriodicalId":7343,"journal":{"name":"Advances in integrative medicine","volume":"12 1","pages":"Pages 7-12"},"PeriodicalIF":1.7000,"publicationDate":"2024-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Advances in integrative medicine","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2212958824001587","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"Medicine","Score":null,"Total":0}

引用次数: 0

Abstract

Introduction

The present study aimed to evaluate the effect of Nano-curcumin on the severity, frequency, and duration of migraine attacks among patients who suffer from this irritating headache.

Methods

PubMed, Scopus, Embase, Web of Science, ProQuest, The Cochrane Library, and google scholar were systematically searched up to December 30, 2022 in order to find the eligible studies investigating the effect of Nano-curcumin supplementation on the duration, severity, or frequency of migraine headache attacks. Only randomized controlled trials were included. RevMan (V 5.4) software was used to perform Meta-analysis and the results were reported using Mean difference with 95 % confidence intervals (CI).

Results

A total of three randomized controlled trials with participation of 126 patients were included. The result of Meta-analysis indicated that using Nano-curcumin supplementation significantly reduced the severity of migraine headache attacks in intervention group [-1.92; 95 % CI (-2.74, −1.09); p < 0.001]; But there was not significant difference in duration [-3.96; 95 % CI (-8.79, 0.89); p = 0.11], and frequency [-1.09; 95 % CI (-2.38, 0.19); p = 0.09] of migraine headache attacks between the intervention and control groups.

Conclusions

Nano-curcumin supplementation in patients suffering from migraine played an important role in reducing severity of migraine headache attacks compared to control group.

查看原文本刊更多论文

求助全文

约1分钟内获得全文求助全文

来源期刊

Advances in integrative medicine INTEGRATIVE & COMPLEMENTARY MEDICINE-

CiteScore

3.20

自引率

11.80%

发文量

审稿时长

15 weeks

期刊介绍： Advances in Integrative Medicine (AIMED) is an international peer-reviewed, evidence-based research and review journal that is multi-disciplinary within the fields of Integrative and Complementary Medicine. The journal focuses on rigorous quantitative and qualitative research including systematic reviews, clinical trials and surveys, whilst also welcoming medical hypotheses and clinically-relevant articles and case studies disclosing practical learning tools for the consulting practitioner. By promoting research and practice excellence in the field, and cross collaboration between relevant practitioner groups and associations, the journal aims to advance the practice of IM, identify areas for future research, and improve patient health outcomes. International networking is encouraged through clinical innovation, the establishment of best practice and by providing opportunities for cooperation between organisations and communities.