Crossing the Boundaries of Conflict: Analyzing Epidemiology & Outcomes of Afghan Oral Squamous Cell Carcinoma Patients at a Pakistani Cancer Hospital.

IF 2.3 3区医学 Q1 OTORHINOLARYNGOLOGY

Head and Neck-Journal for the Sciences and Specialties of the Head and Neck Pub Date : 2025-02-22 DOI:10.1002/hed.28118

Hasnain Haider, Muhammad Awais Kanwal, Muhammad Mohaymin Ali, Afshan Khanum, Shayan Khalid, Kashif Iqbal Malik, Syed Raza Hussain, Muhammad Faisal

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引用次数: 0

Abstract

Background: This study investigates oral cavity squamous cell carcinoma (OSCC) among Afghan patients treated at a Pakistani cancer center, focusing on epidemiology, tumor characteristics, outcomes, and healthcare challenges faced by patients from conflict-affected regions.

Methods: A retrospective analysis of Afghan OSCC patients (2010-2023) was conducted. Demographic, clinical, and treatment data were evaluated, with survival outcomes analyzed using Kaplan-Meier survival analysis.

Results: Of the 117 patients, 47.1% had risk factors, predominantly smokeless tobacco use (61.8%). Tumors were common in oral subsites, especially the tongue (47.86%), with advanced-stage disease (Stage IV) in 34.2%. Mean overall survival was 56.29 months, and mean disease-free survival was 45.54 months. The 5-year overall and disease-free survival rates were 57.7% and 56.5%, respectively.

Conclusion: The study highlights a high prevalence of advanced OSCC, underscoring the need for early detection, public health initiatives, and enhanced cancer care in Afghanistan. International collaboration is essential to improve healthcare access and reduce regional healthcare burdens.

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来源期刊

Head and Neck-Journal for the Sciences and Specialties of the Head and Neck 医学-耳鼻喉科学

CiteScore

7.00

自引率

6.90%

发文量

278

审稿时长

1.6 months

期刊介绍： Head & Neck is an international multidisciplinary publication of original contributions concerning the diagnosis and management of diseases of the head and neck. This area involves the overlapping interests and expertise of several surgical and medical specialties, including general surgery, neurosurgery, otolaryngology, plastic surgery, oral surgery, dermatology, ophthalmology, pathology, radiotherapy, medical oncology, and the corresponding basic sciences.