{"title":"Bilateral Neuroretinitis Following Treatment with Sofosbuvir and Velpatasvir.","authors":"Hitesh Sharma, Jaydeep Walinjkar, Parthopratim Dutta Majumder","doi":"10.1080/09273948.2025.2470902","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose: </strong>We report a case of bilateral neuroretinitis like picture following ingestion of Direct Acting Antivirals (DAAs) in the form of sofosbuvir and velpatasvir, for treatment of Chronic Hepatitis C infection.</p><p><strong>Methods: </strong>retrospective observational case report and review of literature.</p><p><strong>Results: </strong>A healthy 49 years old male, known case of Chronic heptatis C; developed bilateral painless diminution of vision following treatment with DAAs-sofosbuvir and velpatasvir-for treatment-naïve hepatitis C. After thorough work up, ruling out other causes and stopping of medications there was complete resolution of the lesions.</p><p><strong>Conclusion: </strong>Ocular side effects of Direct Acting Antivirals (DAAs) for treatment of Chronic Hepatitis C should be considered, as these are now standard care of treatment for the same.</p>","PeriodicalId":19406,"journal":{"name":"Ocular Immunology and Inflammation","volume":" ","pages":"1-3"},"PeriodicalIF":2.6000,"publicationDate":"2025-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Ocular Immunology and Inflammation","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1080/09273948.2025.2470902","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"OPHTHALMOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Purpose: We report a case of bilateral neuroretinitis like picture following ingestion of Direct Acting Antivirals (DAAs) in the form of sofosbuvir and velpatasvir, for treatment of Chronic Hepatitis C infection.
Methods: retrospective observational case report and review of literature.
Results: A healthy 49 years old male, known case of Chronic heptatis C; developed bilateral painless diminution of vision following treatment with DAAs-sofosbuvir and velpatasvir-for treatment-naïve hepatitis C. After thorough work up, ruling out other causes and stopping of medications there was complete resolution of the lesions.
Conclusion: Ocular side effects of Direct Acting Antivirals (DAAs) for treatment of Chronic Hepatitis C should be considered, as these are now standard care of treatment for the same.
期刊介绍：
Ocular Immunology & Inflammation ranks 18 out of 59 in the Ophthalmology Category.Ocular Immunology and Inflammation is a peer-reviewed, scientific publication that welcomes the submission of original, previously unpublished manuscripts directed to ophthalmologists and vision scientists. Published bimonthly, the journal provides an international medium for basic and clinical research reports on the ocular inflammatory response and its control by the immune system. The journal publishes original research papers, case reports, reviews, letters to the editor, meeting abstracts, and invited editorials.
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