Evoked potentials in patients with disorders of consciousness.

Q2 Medicine

Handbook of clinical neurology Pub Date : 2025-01-01 DOI:10.1016/B978-0-443-13408-1.00002-6

Christoph Leithner, Christian Endisch

{"title":"Evoked potentials in patients with disorders of consciousness.","authors":"Christoph Leithner, Christian Endisch","doi":"10.1016/B978-0-443-13408-1.00002-6","DOIUrl":null,"url":null,"abstract":"<p><p>Acute coma in the intensive care unit and persistent disorders of consciousness (DoC) in neuro-rehabilitation are frequent in patients with hypoxic-ischemic encephalopathy after cardiac arrest (CA), traumatic brain injury, intracranial hemorrhage, or ischemic stroke. Reliable prognostication of long-term neurologic outcomes cannot be made by clinical examination alone in the early phase for many patients, and thus, additional investigations are necessary. Evoked potentials provide inexpensive, real-time, high temporal resolution, bedside, quantifiable information on different sensory pathways into the brain including local and global cortical processing. Short-latency somatosensory evoked potentials can reliably predict poor neurologic long-term outcome in the early phase after CA and are recommended by guidelines as one investigation within an early multimodal assessment. Middle-latency and event-related or cognitive evoked potentials provide information on the integrity of more advanced cortical processing, some closely related to consciousness. This information can help to identify those comatose patients with a good prognosis in the acute phase and help to better understand their precise clinical state and the chances of further recovery in patients with persistent DoC in neuro-rehabilitation. Further studies are necessary to improve the applicability of research findings in the clinical sphere.</p>","PeriodicalId":12907,"journal":{"name":"Handbook of clinical neurology","volume":"207 ","pages":"147-164"},"PeriodicalIF":0.0000,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Handbook of clinical neurology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1016/B978-0-443-13408-1.00002-6","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"Medicine","Score":null,"Total":0}

引用次数: 0

Abstract

Acute coma in the intensive care unit and persistent disorders of consciousness (DoC) in neuro-rehabilitation are frequent in patients with hypoxic-ischemic encephalopathy after cardiac arrest (CA), traumatic brain injury, intracranial hemorrhage, or ischemic stroke. Reliable prognostication of long-term neurologic outcomes cannot be made by clinical examination alone in the early phase for many patients, and thus, additional investigations are necessary. Evoked potentials provide inexpensive, real-time, high temporal resolution, bedside, quantifiable information on different sensory pathways into the brain including local and global cortical processing. Short-latency somatosensory evoked potentials can reliably predict poor neurologic long-term outcome in the early phase after CA and are recommended by guidelines as one investigation within an early multimodal assessment. Middle-latency and event-related or cognitive evoked potentials provide information on the integrity of more advanced cortical processing, some closely related to consciousness. This information can help to identify those comatose patients with a good prognosis in the acute phase and help to better understand their precise clinical state and the chances of further recovery in patients with persistent DoC in neuro-rehabilitation. Further studies are necessary to improve the applicability of research findings in the clinical sphere.

查看原文本刊更多论文

求助全文

约1分钟内获得全文求助全文

来源期刊

Handbook of clinical neurology Medicine-Neurology (clinical)

CiteScore

4.10

自引率

0.00%

发文量

302

期刊介绍： The Handbook of Clinical Neurology (HCN) was originally conceived and edited by Pierre Vinken and George Bruyn as a prestigious, multivolume reference work that would cover all the disorders encountered by clinicians and researchers engaged in neurology and allied fields. The first series of the Handbook (Volumes 1-44) was published between 1968 and 1982 and was followed by a second series (Volumes 45-78), guided by the same editors, which concluded in 2002. By that time, the Handbook had come to represent one of the largest scientific works ever published. In 2002, Professors Michael J. Aminoff, François Boller, and Dick F. Swaab took on the responsibility of supervising the third (current) series, the first volumes of which published in 2003. They have designed this series to encompass both clinical neurology and also the basic and clinical neurosciences that are its underpinning. Given the enormity and complexity of the accumulating literature, it is almost impossible to keep abreast of developments in the field, thus providing the raison d''être for the series. The series will thus appeal to clinicians and investigators alike, providing to each an added dimension. Now, more than 140 volumes after it began, the Handbook of Clinical Neurology series has an unparalleled reputation for providing the latest information on fundamental research on the operation of the nervous system in health and disease, comprehensive clinical information on neurological and related disorders, and up-to-date treatment protocols.