Thomas McGregor , Ewan Carr , Tom Barry , Ana Catarino , Michelle G. Craske , Molly R. Davies , Tim Kerr , Georgina Krebs , Bridie MacDonald , Kirstin L. Purves , Megan Skelton , Ellen J. Thompson , Gerome Breen , Colette R. Hirsch , Thalia C. Eley
{"title":"Self-report measures of fear learning and extinction and their association with internet-based cognitive behavioural therapy outcome","authors":"Thomas McGregor , Ewan Carr , Tom Barry , Ana Catarino , Michelle G. Craske , Molly R. Davies , Tim Kerr , Georgina Krebs , Bridie MacDonald , Kirstin L. Purves , Megan Skelton , Ellen J. Thompson , Gerome Breen , Colette R. Hirsch , Thalia C. Eley","doi":"10.1016/j.brat.2025.104705","DOIUrl":null,"url":null,"abstract":"<div><div>Despite the widespread use of cognitive-behavioural therapy (CBT), only about half of patients respond favourably. Understanding whether relevant psychological processes are associated with treatment response could help identify patients at risk of non-response prior to treatment and improve their outcomes by enabling clinicians to tailor interventions accordingly. Fear conditioning tasks are a valuable tool for studying the learning processes associated with anxiety disorders and their treatment. This study examined associations between outcomes from a remote fear conditioning task and responses to internet-based CBT.</div><div>Anxious adults (n = 112) completed a fear conditioning task before receiving internet-based CBT. Participants rated their expectancy of an aversive noise (unconditioned stimulus; US) in response to a reinforced conditional stimulus (CS+) and a nonreinforced conditional stimulus (CS-) during acquisition, followed by extinction where neither stimulus was reinforced. Anxiety symptoms were assessed before each CBT session. Linear regression models indicated no significant association between mean US-expectancy ratings for 'safe' stimuli (acquisition CS- and extinction CS+) and change in anxiety across treatment. These findings contribute to the mixed literature on fear conditioning's role in treatment outcomes, highlighting the need for further research to elucidate the complex interplay between fear conditioning processes and response to CBT in anxiety disorders.</div></div>","PeriodicalId":48457,"journal":{"name":"Behaviour Research and Therapy","volume":"187 ","pages":"Article 104705"},"PeriodicalIF":4.2000,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Behaviour Research and Therapy","FirstCategoryId":"102","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0005796725000270","RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"PSYCHOLOGY, CLINICAL","Score":null,"Total":0}
引用次数: 0
Abstract
Despite the widespread use of cognitive-behavioural therapy (CBT), only about half of patients respond favourably. Understanding whether relevant psychological processes are associated with treatment response could help identify patients at risk of non-response prior to treatment and improve their outcomes by enabling clinicians to tailor interventions accordingly. Fear conditioning tasks are a valuable tool for studying the learning processes associated with anxiety disorders and their treatment. This study examined associations between outcomes from a remote fear conditioning task and responses to internet-based CBT.
Anxious adults (n = 112) completed a fear conditioning task before receiving internet-based CBT. Participants rated their expectancy of an aversive noise (unconditioned stimulus; US) in response to a reinforced conditional stimulus (CS+) and a nonreinforced conditional stimulus (CS-) during acquisition, followed by extinction where neither stimulus was reinforced. Anxiety symptoms were assessed before each CBT session. Linear regression models indicated no significant association between mean US-expectancy ratings for 'safe' stimuli (acquisition CS- and extinction CS+) and change in anxiety across treatment. These findings contribute to the mixed literature on fear conditioning's role in treatment outcomes, highlighting the need for further research to elucidate the complex interplay between fear conditioning processes and response to CBT in anxiety disorders.
期刊介绍:
The major focus of Behaviour Research and Therapy is an experimental psychopathology approach to understanding emotional and behavioral disorders and their prevention and treatment, using cognitive, behavioral, and psychophysiological (including neural) methods and models. This includes laboratory-based experimental studies with healthy, at risk and subclinical individuals that inform clinical application as well as studies with clinically severe samples. The following types of submissions are encouraged: theoretical reviews of mechanisms that contribute to psychopathology and that offer new treatment targets; tests of novel, mechanistically focused psychological interventions, especially ones that include theory-driven or experimentally-derived predictors, moderators and mediators; and innovations in dissemination and implementation of evidence-based practices into clinical practice in psychology and associated fields, especially those that target underlying mechanisms or focus on novel approaches to treatment delivery. In addition to traditional psychological disorders, the scope of the journal includes behavioural medicine (e.g., chronic pain). The journal will not consider manuscripts dealing primarily with measurement, psychometric analyses, and personality assessment.