Gold clusters: A promising NIR-II probe for bioimaging and biosensing

IF 20.3 1区化学 Q1 CHEMISTRY, INORGANIC & NUCLEAR

Coordination Chemistry Reviews Pub Date : 2025-02-24 DOI:10.1016/j.ccr.2025.216544

Jiaqi Sun , Wanyu Cheng , Xu Liu , Huixin Xiang , Chenhao Ruan , Fenzhen Chen , Chuanhao Yao

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引用次数: 0

Abstract

Optical imaging and biosensing in the second near-infrared window (NIR-II, 1000–1700 nm) have gained significant interest due to their high signal-to-noise ratio (SNR) and excellent spatial and temporal resolution. These features enable accurate monitoring and treatment of deeper bio-pathological processes. Gold nanoclusters (Au NCs) have emerged as promising candidates for NIR-II emission, offering advantages such as their ultra-small size, outstanding biocompatibility, large Stokes shift, and favorable photoluminescence (PL) properties. This review begins by highlighting the benefits and applications of NIR-II luminescent Au NCs in bioimaging and biosensing. We then explore current strategies to enhance the photoluminescence quantum yield (PLQY) of Au NCs, including techniques such as metal doping, ligand engineering, and the aggregation-induced emission (AIE). Furthermore, we discuss advancements in red-shifting the emission wavelength of Au NCs. Our goal is to provide researchers with fresh insights into improving and fine-tuning the photoluminescent properties of Au NCs, thereby broadening their potential applications in NIR-II bioimaging and biosensing.

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来源期刊

Coordination Chemistry Reviews 化学-无机化学与核化学

CiteScore

34.30

自引率

5.30%

发文量

457

审稿时长

54 days

期刊介绍： Coordination Chemistry Reviews offers rapid publication of review articles on current and significant topics in coordination chemistry, encompassing organometallic, supramolecular, theoretical, and bioinorganic chemistry. It also covers catalysis, materials chemistry, and metal-organic frameworks from a coordination chemistry perspective. Reviews summarize recent developments or discuss specific techniques, welcoming contributions from both established and emerging researchers. The journal releases special issues on timely subjects, including those featuring contributions from specific regions or conferences. Occasional full-length book articles are also featured. Additionally, special volumes cover annual reviews of main group chemistry, transition metal group chemistry, and organometallic chemistry. These comprehensive reviews are vital resources for those engaged in coordination chemistry, further establishing Coordination Chemistry Reviews as a hub for insightful surveys in inorganic and physical inorganic chemistry.