Individual effects and interactions between ultrafine particles and extreme temperatures on hospital admissions of high burden diseases

IF 10.3 1区环境科学与生态学 Q1 ENVIRONMENTAL SCIENCES

Environment International Pub Date : 2025-03-01 DOI:10.1016/j.envint.2025.109348

Quan Qi , Yukang Xue , Najm Alsadat Madani , Randy T. Tangang , Fangqun Yu , Arshad Nair , Xiaobo Romeiko Xue , Gan Luo , Isa Brackett , Chris Thorncroft , Shao Lin

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引用次数: 0

Abstract

Background

Health effects of ultrafine particles (UFPs) and their interactions with temperature are less studied. We investigated the risks of UFPs concentrations and extreme temperatures on hospitalizations for high-burden diseases (HBDs) in New York State (NYS).

Methods

This case-crossover study included hospitalizations for HBDs that contain ischemic heart diseases, diabetes, stroke, kidney diseases, and depression using NYS Hospital Discharge Data (2013–2018). Daily pollutants and temperature data were obtained from a chemical transport model validated by multiple prior studies. UFP changes were measured using interquartile range increase, and extreme heat and cold were defined as temperatures >= 90th% and <=10th% respectively by month and location. Conditional logistic regression was applied controlling for criteria pollutants, relative humidity, and time-varying variables.

Results

Among 1,308,518 cases, significant risk ratios (RR) were observed for UFPs (RRs ranged: 1.009–1.012) and extreme heat (RRs ranged: 1.024–1.028) on overall HBDs, but extreme cold had protective effects on HBDs. The adverse effect of UFPs had significant interactions with extreme cold and was higher in winter and fall. UFPs affected all HBD subtypes except kidney diseases, and extreme heat increased the risks of ischemic heart disease and kidney disease. There were disparities across demographics in exposures-HBDs associations although they were not statistically significant. Elevated UFP concentrations were associated with four clinical indicators (hospital stays, charges etc.).

Conclusion

We observe positive associations between elevated UFP concentrations or extreme heat and HBD hospitalizations, but negative associations with extreme cold. The UFPs’ risks were higher in children and during cold seasons.

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来源期刊

Environment International 环境科学-环境科学

CiteScore

21.90

自引率

3.40%

发文量

734

审稿时长

2.8 months

期刊介绍： Environmental Health publishes manuscripts focusing on critical aspects of environmental and occupational medicine, including studies in toxicology and epidemiology, to illuminate the human health implications of exposure to environmental hazards. The journal adopts an open-access model and practices open peer review. It caters to scientists and practitioners across all environmental science domains, directly or indirectly impacting human health and well-being. With a commitment to enhancing the prevention of environmentally-related health risks, Environmental Health serves as a public health journal for the community and scientists engaged in matters of public health significance concerning the environment.