{"title":"Focal Oral Elastosis: Case Series, Proposed Nomenclature, and Literature Review.","authors":"Lama Alabdulaaly, Dahee Chung, Sook-Bin Woo","doi":"10.1097/DAD.0000000000002920","DOIUrl":null,"url":null,"abstract":"<p><strong>Abstract: </strong>Late-onset focal dermal elastosis is an uncommon elastic disorder seen in older individuals and biopsies demonstrate an increase in elastic fibers. Elastosis of the oral cavity is reported uncommonly. The aim of this study is to describe oral biopsies with similar histopathologic features to late-onset focal dermal elastosis and to introduce the term \"focal oral elastosis.\" We included oral biopsies that showed increased elastic fibers confirmed by Verhoeff-van Gieson histochemical stain. We identified 6 oral biopsies with prominent elastosis. There were 4 men, and the median age was 64.5 years. Elastosis was present in 5 nodular lesions and 1 papule. Lesions occurred on the gingiva (33.3%), palatal mucosa (33.3%), buccal mucosa (16.7%), and upper lip (16.7%). Deposition of amorphic bluish/amphophilic material in the subepithelial areas was seen in all cases confirmed with the Verhoeff-van Gieson stain. Our case series demonstrates the presence of elastic fibers in reactive lesions such as oral fibromas.</p>","PeriodicalId":50967,"journal":{"name":"American Journal of Dermatopathology","volume":" ","pages":""},"PeriodicalIF":1.1000,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"American Journal of Dermatopathology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1097/DAD.0000000000002920","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"DERMATOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Abstract: Late-onset focal dermal elastosis is an uncommon elastic disorder seen in older individuals and biopsies demonstrate an increase in elastic fibers. Elastosis of the oral cavity is reported uncommonly. The aim of this study is to describe oral biopsies with similar histopathologic features to late-onset focal dermal elastosis and to introduce the term "focal oral elastosis." We included oral biopsies that showed increased elastic fibers confirmed by Verhoeff-van Gieson histochemical stain. We identified 6 oral biopsies with prominent elastosis. There were 4 men, and the median age was 64.5 years. Elastosis was present in 5 nodular lesions and 1 papule. Lesions occurred on the gingiva (33.3%), palatal mucosa (33.3%), buccal mucosa (16.7%), and upper lip (16.7%). Deposition of amorphic bluish/amphophilic material in the subepithelial areas was seen in all cases confirmed with the Verhoeff-van Gieson stain. Our case series demonstrates the presence of elastic fibers in reactive lesions such as oral fibromas.
期刊介绍：
The American Journal of Dermatopathology offers outstanding coverage of the latest diagnostic approaches and laboratory techniques, as well as insights into contemporary social, legal, and ethical concerns. Each issue features review articles on clinical, technical, and basic science advances and illuminating, detailed case reports.
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