Heng He, Zihan Zhang, Zhenzhen Li, Sisi Jiang, Lijun Zhen, Jianmiao Mo, Yufei Zhang, Yan Wei, Mengna Wu, Xuerong Su, Changyong Wan, Rongxiang Li, Na Wan, Xiuhong Fu, Weihong Qiu
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引用次数: 0
Abstract
Introduction: The short-term effects of exposure to fine particulate matter (PM2.5) and its five components (sulfate, nitrate, ammonium salt, organic matter [OM], and black carbon [BC]) on hospitalizations for hypertensive disorders of pregnancy (HDP) remains unclear.
Methods: This study enrolled mothers with HDP from January 1, 2015, to December 31, 2021, in five cities in Henan Province, China. Daily data on PM2.5 were obtained from the Tracking Air Pollution in China, an online public dataset. Time-stratified case-crossover models were performed to assess the short-term single-day (lag0-1) and multi-day (lag01-07) lag effects of PM2.5 on hospitalizations for HDP and further explored the modification effects of maternal age (<35 years and ≥35 years), season (cold and warm seasons), and the "Three-Year Action Plan to Win the Blue Sky Defense War (before and after June 27, 2018) on the short-term effects.
Results: A total of 8,007 mothers with HDP were recruited. An IQR in exposure to PM2.5, OM, and BC, was associated with 5.7% (RR: 1.057, 95% CI: 1.002-1.112) (lag01), 6.4% (1.064,1.003-1.126) (lag01), and 6.8% (1.068, 1.001-1.135) (lag05) increases in the risk of HDP, respectively (all P<0.05). The effects of exposure to PM2.5 and its components were stronger in mothers aged ≥35 years, in the cold season, and in the period before the Action Plan was implemented (Pmodification<0.05).
Conclusion: Short-term exposure to PM2.5 and its components was positively associated with hospitalizations for HDP, particularly among mothers aged ≥35 years, during the cold season and before the implementation of the Action Plan.
期刊介绍:
The American Journal of Preventive Medicine is the official journal of the American College of Preventive Medicine and the Association for Prevention Teaching and Research. It publishes articles in the areas of prevention research, teaching, practice and policy. Original research is published on interventions aimed at the prevention of chronic and acute disease and the promotion of individual and community health.
Of particular emphasis are papers that address the primary and secondary prevention of important clinical, behavioral and public health issues such as injury and violence, infectious disease, women''s health, smoking, sedentary behaviors and physical activity, nutrition, diabetes, obesity, and substance use disorders. Papers also address educational initiatives aimed at improving the ability of health professionals to provide effective clinical prevention and public health services. Papers on health services research pertinent to prevention and public health are also published. The journal also publishes official policy statements from the two co-sponsoring organizations, review articles, media reviews, and editorials. Finally, the journal periodically publishes supplements and special theme issues devoted to areas of current interest to the prevention community.