A Portuguese expert panel position paper on the management of heart failure with preserved ejection fraction – Part I: Pathophysiology, diagnosis and treatment

IF 1.6 4区医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS

Revista Portuguesa De Cardiologia Pub Date : 2025-04-01 DOI:10.1016/j.repc.2024.11.011

José Silva-Cardoso , Emília Moreira , Rachel Tavares de Melo , Pedro Moraes-Sarmento , Nuno Cardim , Mário Oliveira , Cristina Gavina , Brenda Moura , Inês Araújo , Paulo Santos , Marisa Peres , Cândida Fonseca , João Pedro Ferreira , Irene Marques , Aurora Andrade , Rui Baptista , Dulce Brito , Rui Cernadas , Jonathan dos Santos , Adelino Leite-Moreira , Joana Pimenta

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引用次数: 0

Abstract

Heart failure (HF) with preserved ejection fraction (HFpEF) affects more than 50% of HF patients worldwide, and more than 70% of HF patients aged over 65. This is a complex syndrome with a clinically heterogeneous presentation and a multifactorial pathophysiology, both of which make its diagnosis and treatment challenging.

A Portuguese HF expert panel convened to address HFpEF pathophysiology and therapy, as well as appropriate management within the Portuguese context. This initiative resulted in two position papers that examine the most recently published literature in the field.

The present Part I includes a review of the HFpEF literature covering pathophysiology, clinical presentation, diagnosis and treatment, including pharmacological and non-pharmacological strategies.

Part II, the second paper, addresses the development of a holistic and integrated HFPEF clinical care system within the Portuguese context that is capable of reducing morbidity and mortality and improving patients’ functional capacity and quality of life.

查看原文本刊更多论文

葡萄牙专家小组关于保留射血分数的心力衰竭管理的立场文件-第一部分：病理生理学，诊断和治疗。

心力衰竭伴射血分数保留（HFpEF）影响全球超过50%的HF患者，超过70%的65岁以上的HF患者。这是一种复杂的综合征，具有临床异质性和多因素病理生理学，这两者都使其诊断和治疗具有挑战性。葡萄牙HF专家小组召开会议，讨论HFpEF的病理生理和治疗，以及葡萄牙环境下的适当管理。这一倡议产生了两份立场文件，审查了该领域最近发表的文献。目前的第一部分包括对HFpEF文献的回顾，包括病理生理学，临床表现，诊断和治疗，包括药物和非药物策略。第二部分，第二篇论文，在葡萄牙的背景下，解决了一个整体和综合的HFPEF临床护理系统的发展，能够降低发病率和死亡率，提高患者的功能能力和生活质量。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Revista Portuguesa De Cardiologia CARDIAC & CARDIOVASCULAR SYSTEMS-

CiteScore

2.70

自引率

22.20%

发文量

205

审稿时长

54 days

期刊介绍： The Portuguese Journal of Cardiology, the official journal of the Portuguese Society of Cardiology, was founded in 1982 with the aim of keeping Portuguese cardiologists informed through the publication of scientific articles on areas such as arrhythmology and electrophysiology, cardiovascular surgery, intensive care, coronary artery disease, cardiovascular imaging, hypertension, heart failure and cardiovascular prevention. The Journal is a monthly publication with high standards of quality in terms of scientific content and production. Since 1999 it has been published in English as well as Portuguese, which has widened its readership abroad. It is distributed to all members of the Portuguese Societies of Cardiology, Internal Medicine, Pneumology and Cardiothoracic Surgery, as well as to leading non-Portuguese cardiologists and to virtually all cardiology societies worldwide. It has been referred in Medline since 1987.