Survey of antibiotic use at a tertiary care hospital in Mexico.

IF 2.4 4区医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

Salud Publica De Mexico Pub Date : 2025-02-20 DOI:10.21149/16283

Federico A Zumaya-Estrada, Hilda Ivonne Huerta-Icelo, Estaban González-Díaz, María Del Rayo Morfín-Otero, Jesús Ulises Garza-Ramos, Celia Mercedes Alpuche-Aranda

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引用次数: 0

Abstract

Objective: To analyze antibiotic use in a tertiary care hospital in Mexico.

Materials and methods: We conducted two point prevalence surveys based on the World Health Organization methodology in a tertiary care hospital in Guadalajara, Mexico. We surveyed the clinical records of patients with active antibiotic prescriptions (APs) in medical (MED), surgical (SUR), medical-surgical (MIX) wards, and intensive care units (ICUs). Descriptive statistics were estimated using Stata software.

Results: We analyzed 929 APs from 403 patients. The prevalence of antibiotic use in the hospital was 47.5%. Antibiotics were more used in ICUs (59.5%) and MIX wards (54.8%). The main reasons for antibiotic use were community-acquired infections (45.2%), and preoperative prophylaxis (23.1%), mostly multidose and prolonged (89.3%). APs were mainly empirical (92.4%), administered parenterally (95.9%) and lacked subsequent review (30.3%). Bacterial culture testing was limited (30.5%). The most used antibiotics were ceftriaxone (18.9%), clindamycin (8.5%), and meropenem (8.2%). Most APs corresponded to Access (56.4%) and Watch antibiotics (35.6%) (AWaRe, WHO).

Conclusions: We revealed frequent prescribing patterns of broad-spectrum antibiotics and differences in their use possibly related to patients' clinical profiles.

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墨西哥一家三级医院抗生素使用情况调查。

目的：分析墨西哥某三级医院抗生素使用情况。材料和方法：我们根据世界卫生组织的方法在墨西哥瓜达拉哈拉的一家三级保健医院进行了两点患病率调查。我们调查了内科（MED）、外科（SUR）、内科-外科（MIX）病房和重症监护病房（ICUs）中使用有效抗生素处方（APs）的患者的临床记录。描述性统计使用Stata软件进行估计。结果：我们分析了403例患者的929例ap。该院抗生素使用率为47.5%。icu（59.5%）和MIX病房（54.8%）使用抗生素较多。抗生素使用的主要原因是社区获得性感染（45.2%）和术前预防（23.1%），多剂量和长期预防（89.3%）为主。ap主要是经验性的（92.4%），肠外给药（95.9%），缺乏后续评价（30.3%）。细菌培养检测有限（30.5%）。使用最多的抗生素是头孢曲松（18.9%）、克林霉素（8.5%）和美罗培南（8.2%）。大多数ap对应于获取抗生素（56.4%）和观察抗生素（35.6%）（AWaRe， WHO）。结论：我们揭示了广谱抗生素的常见处方模式及其使用差异可能与患者的临床资料有关。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Salud Publica De Mexico PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-

CiteScore

3.30

自引率

21.70%

发文量

审稿时长

34 weeks

期刊介绍： Salud Pública de México se crea en 1959 y comienza a publicarse bimestralmente a partir de 1961; en 1988 inicia una nueva época en la que se refuerza su carácter de publicación científica con evaluación por pares. Es una revista publicada por el Instituto Nacional de Salud Pública (INSP), organismo descentralizado de la Secretaría de Salud de México, dedicado a la investigación, docencia y difusión del conocimiento en salud pública. El INSP, de acuerdo con la normatividad internacional, otorga a la revista independencia editorial.