Clinical and pathological characteristics of pulmonary meningioma: a case report and literature review.

Abstract

This case report aimed to examine the clinical pathological characteristics, immunohistochemical phenotype, and differential diagnosis of primary pulmonary meningioma (PM), which is a rare tumor. A retrospective analysis was conducted on the clinical data, imaging manifestations, histological features, immunohistochemical results, and in situ hybridization results of a 60-year-old male patient who underwent surgical resection and was diagnosed with PM by pathology. Additionally, the relevant literature was reviewed. Multiple nodules were detected in the right lung of the patient during a re-examination because of a novel coronavirus infection but there were no obvious clinical symptoms. Imaging revealed well-defined masses in the upper, middle, and lower lobes of the right lung, and the masses were surgically removed. Microscopy showed that the boundary between the tumor and surrounding lung tissue was clear, and consisted of spindle cells and epithelioid cells. The final diagnosis was multiple grade II meningiomas of the right lung. No postoperative radiotherapy or chemotherapy was performed. There was no recurrence or metastasis during a 6-month follow-up. Pulmonary metastatic meningioma is rare, while primary PM is even rarer. Surgical resection is the preferred treatment method for PM, with a generally good prognosis, but a few malignant manifestations may require close follow-up.