Analysis of Superb Microvascular Imaging Blood Flow Scoring, Disease Duration, and Laboratory Indicators Involved in Gout.

IF 1.2 4区 医学 Q3 ACOUSTICS
Jianming Lu, Qian Zhang, Guangfei Yang, Zhile Gu, Yating Wu
{"title":"Analysis of Superb Microvascular Imaging Blood Flow Scoring, Disease Duration, and Laboratory Indicators Involved in Gout.","authors":"Jianming Lu, Qian Zhang, Guangfei Yang, Zhile Gu, Yating Wu","doi":"10.1002/jcu.23940","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose: </strong>To investigate the correlation among semi-quantitative scoring of blood flow by superb microvascular imaging (SMI), hypersensitive C-reactive protein (hs-CRP), erythrocyte sedimentation rate (ESR), and serum uric acid (SUA) levels in different gout duration.</p><p><strong>Methods: </strong>103 patients (total 157 affected joints) with clinically confirmed acute gout attack from January 2021 to May 2022 were performed with laboratory tests (hs-CRP, ESR, SUA), routine joint ultrasound scanning, along with semi-quantitative scoring of SMI, and correlations between which were analyzed.</p><p><strong>Results: </strong>Statistically significant differences were found in semi-quantitative scoring of SMI in the affected joints between different disease duration. The differences between SMI scoring in gouty tophi, synovial hyperplasia, and the levels of different hs-CRP and ESR subgroups of the affected joints were statistically significant (p < 0.05). R values between SMI scoring in synovial hyperplasia as well as gouty tophi and hs-CRP levels were 0.711 and 0.579, respectively, and those of ESR were 0.430 and 0.418, respectively, while those of SUA levels were -0.227 and 0.120, respectively.</p><p><strong>Conclusion: </strong>With a prolonged progression of gout, hs-CRP and ESR levels amplify, along with a concurrent intensification in the SMI scorings of blood flow signals in the affected joints (grades 2 and 3). In the acute gout attack, SMI blood flow scoring showed a moderate correlation to hs-CRP, a low correlation to ESR, and no correlation to SUA, among which the best correlation was found between SMI scoring and hs-CRP levels in the synovial hyperplasia.</p>","PeriodicalId":15386,"journal":{"name":"Journal of Clinical Ultrasound","volume":" ","pages":""},"PeriodicalIF":1.2000,"publicationDate":"2025-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Clinical Ultrasound","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1002/jcu.23940","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"ACOUSTICS","Score":null,"Total":0}
引用次数: 0

Abstract

Purpose: To investigate the correlation among semi-quantitative scoring of blood flow by superb microvascular imaging (SMI), hypersensitive C-reactive protein (hs-CRP), erythrocyte sedimentation rate (ESR), and serum uric acid (SUA) levels in different gout duration.

Methods: 103 patients (total 157 affected joints) with clinically confirmed acute gout attack from January 2021 to May 2022 were performed with laboratory tests (hs-CRP, ESR, SUA), routine joint ultrasound scanning, along with semi-quantitative scoring of SMI, and correlations between which were analyzed.

Results: Statistically significant differences were found in semi-quantitative scoring of SMI in the affected joints between different disease duration. The differences between SMI scoring in gouty tophi, synovial hyperplasia, and the levels of different hs-CRP and ESR subgroups of the affected joints were statistically significant (p < 0.05). R values between SMI scoring in synovial hyperplasia as well as gouty tophi and hs-CRP levels were 0.711 and 0.579, respectively, and those of ESR were 0.430 and 0.418, respectively, while those of SUA levels were -0.227 and 0.120, respectively.

Conclusion: With a prolonged progression of gout, hs-CRP and ESR levels amplify, along with a concurrent intensification in the SMI scorings of blood flow signals in the affected joints (grades 2 and 3). In the acute gout attack, SMI blood flow scoring showed a moderate correlation to hs-CRP, a low correlation to ESR, and no correlation to SUA, among which the best correlation was found between SMI scoring and hs-CRP levels in the synovial hyperplasia.

求助全文
约1分钟内获得全文 求助全文
来源期刊
CiteScore
1.90
自引率
0.00%
发文量
248
审稿时长
6 months
期刊介绍: The Journal of Clinical Ultrasound (JCU) is an international journal dedicated to the worldwide dissemination of scientific information on diagnostic and therapeutic applications of medical sonography. The scope of the journal includes--but is not limited to--the following areas: sonography of the gastrointestinal tract, genitourinary tract, vascular system, nervous system, head and neck, chest, breast, musculoskeletal system, and other superficial structures; Doppler applications; obstetric and pediatric applications; and interventional sonography. Studies comparing sonography with other imaging modalities are encouraged, as are studies evaluating the economic impact of sonography. Also within the journal''s scope are innovations and improvements in instrumentation and examination techniques and the use of contrast agents. JCU publishes original research articles, case reports, pictorial essays, technical notes, and letters to the editor. The journal is also dedicated to being an educational resource for its readers, through the publication of review articles and various scientific contributions from members of the editorial board and other world-renowned experts in sonography.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信