Treatment of Chronic-Relapsing Pitted Keratolysis with Glycopyrronium Bromide Cream: Case Report.

IF 0.9 Q4 DERMATOLOGY
Case Reports in Dermatology Pub Date : 2024-11-25 eCollection Date: 2025-01-01 DOI:10.1159/000542484
Stefano Veraldi, Rossana Schianchi, Italo Francesco Aromolo, Gianluca Nazzaro
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引用次数: 0

Abstract

Introduction: Pitted keratolysis (PK) is a superficial bacterial infection located almost exclusively on the soles. The most important predisposing factor is hyperhidrosis. PK is characterized by small, isolated or confluent, crateriform, noninflammatory pits. Maceration and malodor are the two most important signs and symptoms. The therapy of PK is very often unsatisfactory.

Case presentation: Two patients with chronic-relapsing PK were successfully treated with a cream containing 1% glycopyrronium bromide, a new topical anticholinergic with anti-hyperhidrosis action.

Conclusions: Although our experience is currently based on only 2 patients, glycopyrronium bromide cream can be taken into consideration for prevention of chronic-relapsing PK.

甘溴化铵乳膏治疗慢性复发性凹陷性角化1例。
导读:凹陷性角化(PK)是一种几乎完全位于鞋底的浅表细菌感染。最重要的诱发因素是多汗症。PK的特点是小的,孤立的或汇合的,不规则的,非炎症性的小坑。浸渍和恶臭是两个最重要的迹象和症状。PK的治疗往往不令人满意。病例介绍:两例慢性复发PK患者成功治疗乳膏含有1%甘溴铵,一种新的局部抗胆碱能抗多汗症的作用。结论:虽然我们目前的经验仅基于2例患者,但可以考虑使用溴化甘溴铵乳膏预防慢性复发性PK。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
1.60
自引率
0.00%
发文量
57
审稿时长
9 weeks
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