Addressing Diagnostic and Therapeutic Challenges in a Case of Concurrent Tinea and Plaque Psoriasis.

IF 0.9 Q4 DERMATOLOGY
Case Reports in Dermatology Pub Date : 2024-11-19 eCollection Date: 2024-01-01 DOI:10.1159/000542483
Divya Asnani, Shrishti Singh, Aayush Gupta
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Abstract

Introduction: The annular lesions of dermatophytosis can closely resemble the plaques of psoriasis, posing significant diagnostic and treatment challenges. Methotrexate, a common treatment for psoriasis, can exacerbate the former due to its immunosuppressive effects.

Case report: ​​A middle-aged man with chronic plaque psoriasis was on tablet methotrexate (7.5 mg once weekly) and topical steroids for 1 year. Despite some improvement, new annular lesions emerged whenever topical steroids were tapered. Frustrated with the lack of disease control, the patient finally visited a tertiary care center, where tinea corporis was diagnosed alongside psoriasis via dermoscopy, mycological tests, and histopathology. Methotrexate and steroids were discontinued, and the patient was started on antifungals. Once the dermatophytosis was brought under control, methotrexate was resumed alongside targeted application of steroid and antifungal creams.

Conclusion: The coexistence of tinea corporis and psoriasis can be challenging to diagnose and treat, necessitating thorough clinical evaluation and mycological testing. Proactive monitoring and timely intervention are crucial to prevent complications and ensure optimal management outcomes in immunosuppressed individuals with dermatophyte infections.

解决并发癣和斑块银屑病的诊断和治疗挑战。
摘要:皮肤真菌病的环形病变与牛皮癣的斑块非常相似,对诊断和治疗提出了重大挑战。甲氨蝶呤是银屑病的常用治疗方法,由于其免疫抑制作用,可使前者恶化。病例报告:一名患有慢性斑块型银屑病的中年男性服用甲氨蝶呤片剂(7.5 mg,每周一次)和局部类固醇治疗1年。尽管有一些改善,但每当局部类固醇逐渐减少时,新的环状病变就会出现。由于缺乏疾病控制,患者最终前往三级保健中心,在那里通过皮肤镜检查、真菌学检查和组织病理学诊断为体癣和牛皮癣。停用甲氨蝶呤和类固醇,并开始使用抗真菌药物。一旦皮肤真菌病得到控制,甲氨蝶呤恢复与类固醇和抗真菌药膏的靶向应用。结论:体癣合并银屑病的诊断和治疗具有一定的挑战性,需要进行全面的临床评估和真菌学检测。主动监测和及时干预是至关重要的,以防止并发症和确保最佳的管理结果免疫抑制个体皮肤真菌感染。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
1.60
自引率
0.00%
发文量
57
审稿时长
9 weeks
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