{"title":"A Cross-sectional Study for the Correlation of Vitamin D Level and Severity of Early Rheumatoid Arthritis.","authors":"Sudipto Chakraborty, Mohidur Rahaman, Pradip Dey, Shreya Choudhury, Rajeswar Samanta, Swagatam Sengupta, Parineeta Singhal, Siktha Purkait, Sakshi Puri, Insha Aleena, Dhiman Sen","doi":"10.4103/aam.aam_205_24","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Rheumatoid arthritis (RA) is a chronic inflammatory multisystemic disorder that can cause significant deformity and disability. Vitamin D has a role in Th1-medicated autoimmune diseases like RA. Furthermore, some observational studies have concluded that Vitamin D supplementation reduces the severity of RA.</p><p><strong>Aims: </strong>This study aimed to find out any correlation between Vitamin D levels and severity of early RA.</p><p><strong>Settings and design: </strong>This study settings and design were a cross-sectional single-center observational study.</p><p><strong>Materials and methods: </strong>This was an observational study. All patients with early RA were screened and evaluated as per protocol. No extra tests were done.</p><p><strong>Statistical analysis used: </strong>Pearson's Chi-square test for independence of attributes/Fisher's exact test was used to find the association between the categorical variables as appropriate.</p><p><strong>Results and conclusion: </strong>We found that all patients of early RA had moderate-tosevere disease activity without any relation with their Vitamin D level (P > 0.05).</p>","PeriodicalId":7938,"journal":{"name":"Annals of African Medicine","volume":" ","pages":""},"PeriodicalIF":0.6000,"publicationDate":"2025-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Annals of African Medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4103/aam.aam_205_24","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
引用次数: 0
Abstract
Background: Rheumatoid arthritis (RA) is a chronic inflammatory multisystemic disorder that can cause significant deformity and disability. Vitamin D has a role in Th1-medicated autoimmune diseases like RA. Furthermore, some observational studies have concluded that Vitamin D supplementation reduces the severity of RA.
Aims: This study aimed to find out any correlation between Vitamin D levels and severity of early RA.
Settings and design: This study settings and design were a cross-sectional single-center observational study.
Materials and methods: This was an observational study. All patients with early RA were screened and evaluated as per protocol. No extra tests were done.
Statistical analysis used: Pearson's Chi-square test for independence of attributes/Fisher's exact test was used to find the association between the categorical variables as appropriate.
Results and conclusion: We found that all patients of early RA had moderate-tosevere disease activity without any relation with their Vitamin D level (P > 0.05).
期刊介绍:
The Annals of African Medicine is published by the Usmanu Danfodiyo University Teaching Hospital, Sokoto, Nigeria and the Annals of African Medicine Society. The Journal is intended to serve as a medium for the publication of research findings in the broad field of Medicine in Africa and other developing countries, and elsewhere which have relevance to Africa. It will serve as a source of information on the state of the art of Medicine in Africa, for continuing education for doctors in Africa and other developing countries, and also for the publication of meetings and conferences. The journal will publish articles I any field of Medicine and other fields which have relevance or implications for Medicine.