Preoperative haemoglobin as a predictor of in-hospital morbidity and 5-year mortality in colorectal cancer.

Revista espanola de anestesiologia y reanimacion Pub Date : 2025-02-17 DOI:10.1016/j.redare.2025.501723

A Herrero García, S E Denis Filippini, A de la Fuente, E Choolani Bhojwani, J Sánchez González, M Bailón Cuadrado, S Veleda Belanche, V Simó Fernández, J A García Erce, C Aldecoa Álvarez-Santullano

{"title":"Preoperative haemoglobin as a predictor of in-hospital morbidity and 5-year mortality in colorectal cancer.","authors":"A Herrero García, S E Denis Filippini, A de la Fuente, E Choolani Bhojwani, J Sánchez González, M Bailón Cuadrado, S Veleda Belanche, V Simó Fernández, J A García Erce, C Aldecoa Álvarez-Santullano","doi":"10.1016/j.redare.2025.501723","DOIUrl":null,"url":null,"abstract":"Background: Colorectal cancer (CRC) is the third most diagnosed cancer worldwide. Preoperative anaemia is common in CRC patients undergoing surgery.Objective: This study assesses the prevalence of preoperative anaemia and its impact on postoperative outcomes, and aims to establish a cut-off point for increased morbidity and mortality in a large prospective single centre cohort.Methods: We conducted a retrospective cohort study of 1105 CRC patients (2014-2021). Anaemia was defined as per WHO criteria. Multivariate logistic regression and Kaplan-Meier survival analyses were used. The statistical significance level was set at <0.05.Results: Preoperative anaemia was present in 45.3% of patients, and was associated with a higher incidence of perioperative complications (OR 2.76, p = 0.011) and lower 5-year survival (73% vs 87%, p < 0.001.Discussion/conclusions: Preoperative anaemia, even when mild, is associated with a higher rate of complications, longer hospital stay, and a greater risk of 5-year mortality.","PeriodicalId":94196,"journal":{"name":"Revista espanola de anestesiologia y reanimacion","volume":" ","pages":"501723"},"PeriodicalIF":0.0000,"publicationDate":"2025-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Revista espanola de anestesiologia y reanimacion","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1016/j.redare.2025.501723","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 0

Abstract

Background: Colorectal cancer (CRC) is the third most diagnosed cancer worldwide. Preoperative anaemia is common in CRC patients undergoing surgery.

Objective: This study assesses the prevalence of preoperative anaemia and its impact on postoperative outcomes, and aims to establish a cut-off point for increased morbidity and mortality in a large prospective single centre cohort.

Methods: We conducted a retrospective cohort study of 1105 CRC patients (2014-2021). Anaemia was defined as per WHO criteria. Multivariate logistic regression and Kaplan-Meier survival analyses were used. The statistical significance level was set at <0.05.

Results: Preoperative anaemia was present in 45.3% of patients, and was associated with a higher incidence of perioperative complications (OR 2.76, p = 0.011) and lower 5-year survival (73% vs 87%, p < 0.001.

Discussion/conclusions: Preoperative anaemia, even when mild, is associated with a higher rate of complications, longer hospital stay, and a greater risk of 5-year mortality.

查看原文本刊更多论文

求助全文

约1分钟内获得全文求助全文

来源期刊

Revista espanola de anestesiologia y reanimacion

自引率

0.00%

发文量