The risk of epilepsy following neonatal seizures

IF 3.8 2区 医学 Q1 CLINICAL NEUROLOGY
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Abstract

One of the most frequent acute neurological conditions among infants admitted to a neonatal intensive care unit is seizures. Seizures in the neonatal period can be caused by many different conditions, such as lack of oxygen to the brain before, during, and right after birth (asphyxia); cerebral stroke; or cerebral infection. A frequent question asked by parents after the seizures have ceased is whether they will return at some point during childhood.

In this study we examine the risk of epilepsy among children with neonatal seizures compared to children who have not had seizures during neonatal life, and we examine whether the risk of epilepsy differs between conditions known to cause seizures in the neonatal period. The study is based on registry data including all children born in Denmark between 1997 and 2018. We followed a total of 1 294 377 children of whom 1998 have had seizures in the neonatal period. Follow-up period was 22 years.

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来源期刊
CiteScore
7.80
自引率
13.20%
发文量
338
审稿时长
3-6 weeks
期刊介绍: Wiley-Blackwell is pleased to publish Developmental Medicine & Child Neurology (DMCN), a Mac Keith Press publication and official journal of the American Academy for Cerebral Palsy and Developmental Medicine (AACPDM) and the British Paediatric Neurology Association (BPNA). For over 50 years, DMCN has defined the field of paediatric neurology and neurodisability and is one of the world’s leading journals in the whole field of paediatrics. DMCN disseminates a range of information worldwide to improve the lives of disabled children and their families. The high quality of published articles is maintained by expert review, including independent statistical assessment, before acceptance.
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