The risk of epilepsy following neonatal seizures

IF 3.8 2区 医学 Q1 CLINICAL NEUROLOGY
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Abstract

One of the most frequent acute neurological conditions among infants admitted to a neonatal intensive care unit is seizures. Seizures in the neonatal period can be caused by many different conditions, such as lack of oxygen to the brain before, during, and right after birth (asphyxia); cerebral stroke; or cerebral infection. A frequent question asked by parents after the seizures have ceased is whether they will return at some point during childhood.

In this study we examine the risk of epilepsy among children with neonatal seizures compared to children who have not had seizures during neonatal life, and we examine whether the risk of epilepsy differs between conditions known to cause seizures in the neonatal period. The study is based on registry data including all children born in Denmark between 1997 and 2018. We followed a total of 1 294 377 children of whom 1998 have had seizures in the neonatal period. Follow-up period was 22 years.

Abstract Image

新生儿癫痫发作后癫痫的风险。
新生儿重症监护病房收治的婴儿中最常见的急性神经系统疾病之一是癫痫发作。新生儿时期的癫痫发作可由许多不同的情况引起,例如在出生前、出生时和出生后大脑缺氧(窒息);脑卒中;或者是脑部感染。在癫痫发作停止后,父母经常问的一个问题是,他们是否会在儿童时期的某个时候再次发作。在这项研究中,我们检查了新生儿癫痫发作的儿童与在新生儿时期没有癫痫发作的儿童的癫痫风险,我们检查了癫痫的风险在新生儿时期已知的引起癫痫发作的条件之间是否存在差异。该研究基于登记数据,包括1997年至2018年在丹麦出生的所有儿童。我们对1 294 377名儿童进行了随访,其中1998名儿童在新生儿期出现癫痫发作。随访22年。
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来源期刊
CiteScore
7.80
自引率
13.20%
发文量
338
审稿时长
3-6 weeks
期刊介绍: Wiley-Blackwell is pleased to publish Developmental Medicine & Child Neurology (DMCN), a Mac Keith Press publication and official journal of the American Academy for Cerebral Palsy and Developmental Medicine (AACPDM) and the British Paediatric Neurology Association (BPNA). For over 50 years, DMCN has defined the field of paediatric neurology and neurodisability and is one of the world’s leading journals in the whole field of paediatrics. DMCN disseminates a range of information worldwide to improve the lives of disabled children and their families. The high quality of published articles is maintained by expert review, including independent statistical assessment, before acceptance.
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