Association of macular sensitivity with posterior staphyloma in highly myopic eyes: Aier-SERI high myopia adult cohort study.

IF 2.8 3区 医学 Q1 OPHTHALMOLOGY
Ophthalmic and Physiological Optics Pub Date : 2025-05-01 Epub Date: 2025-02-20 DOI:10.1111/opo.13467
Yanfeng Jiang, Li-Lian Foo, Ziqi Hu, Wei Pan, Kai-Xiong Cheong, Huanhuan Tan, Seang-Mei Saw, Quan V Hoang, Zhikuan Yang, Weizhong Lan
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引用次数: 0

Abstract

Purpose: The purpose of this study was to determine the relationship between macular sensitivity (MS) and posterior staphyloma (PS) in highly myopic eyes.

Methods: This cross-sectional, observational study included 646 highly myopic eyes (spherical equivalent (SE) ≤-5.00D and the international meta-analysis for pathologic myopia classification grade of <2) from 362 participants. MS was measured using microperimetry and evaluated between eyes with and without PS. Correlations between MS and PS were determined in multivariate regression models.

Results: Although there was no significant difference in best-corrected visual acuity (BCVA) (p = 0.07), the MS of the PS group was significantly lower than the no PS group at the central 2°, 4°, 6°, 8° and 10° (all p < 0.001). After controlling age, axial length (AL) and SE, the MS in the PS group was still lower than the no PS group from 2° to 10° (all p < 0.05). In a multivariable analysis adjusting for age, AL, SE and BCVA, the presence of PS was significantly associated with lower MS in the central 2°-10° (all p < 0.05).

Conclusions: Lower MS was independently associated with the presence of PS in highly myopic eyes. Even when BCVA was not significantly different, MS still could reveal subtle changes in visual function in highly myopic eyes with PS.

高度近视眼黄斑敏感性与后葡萄肿的关系:Aier-SERI高度近视成人队列研究。
目的:本研究的目的是确定高度近视眼黄斑敏感性(MS)与后葡萄肿(PS)之间的关系。方法:采用横断面观察性研究,纳入646只高度近视眼(球面等效度(SE)≤-5.00D),并对病理性近视分级进行国际meta分析。结果:虽然最佳矫正视力(BCVA)无显著差异(p = 0.07),但PS组在中心2°、4°、6°、8°和10°处的MS显著低于无PS组(均p)。低MS与高度近视眼PS的存在独立相关。即使在BCVA无显著差异的情况下,MS仍能显示高度近视伴PS的视功能的细微变化。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
5.10
自引率
13.80%
发文量
135
审稿时长
6-12 weeks
期刊介绍: Ophthalmic & Physiological Optics, first published in 1925, is a leading international interdisciplinary journal that addresses basic and applied questions pertinent to contemporary research in vision science and optometry. OPO publishes original research papers, technical notes, reviews and letters and will interest researchers, educators and clinicians concerned with the development, use and restoration of vision.
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