Significance of an Early Diagnosis of Autoimmune Gastritis in Nonelderly Patients with Type 1 Diabetes Mellitus and Autoimmune Thyroid Disease.

IF 1.1 4区医学 Q3 MEDICINE, GENERAL & INTERNAL

Internal Medicine Pub Date : 2025-09-01 Epub Date: 2025-02-18 DOI:10.2169/internalmedicine.4552-24

Tomoya Katayama, Naoko Nakanishi, Hiroyuki Inagake, Emiko Wada, Aya Kitae, Naoto Nakamura, Michiaki Fukui

引用次数: 0

Abstract

A 45-year-old woman with Basedow's disease, who was later diagnosed with slowly progressive type 1 diabetes mellitus (SPIDDM), developed iron deficiency anemia. Despite normal vitamin B12 levels, the endoscopic findings of the residual fundic glands and severe atrophy predominantly in the body of the stomach and fundus, along with serological tests, confirmed a diagnosis of autoimmune gastritis (AIG). This case highlights the significance of an early AIG diagnosis in non-elderly patients with type 1 diabetes mellitus (T1DM) and autoimmune thyroid disease (AITD) because of the risk of developing pernicious anemia and gastric neoplasms.

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非老年1型糖尿病合并自身免疫性甲状腺疾病患者自身免疫性胃炎早期诊断的意义1例

一名45岁的妇女患有巴塞多氏病，后来被诊断为缓慢进展型1型糖尿病（SPIDDM），并发缺铁性贫血。尽管维生素B12水平正常，但内镜检查发现残留的底腺体和主要在胃和底的严重萎缩，以及血清学检查，证实了自身免疫性胃炎（AIG）的诊断。该病例强调了早期AIG诊断对非老年1型糖尿病（T1DM）和自身免疫性甲状腺疾病（AITD）患者的重要性，因为它们有发展为恶性贫血和胃肿瘤的风险。关键词：缓慢进展型1型糖尿病（SPIDDM）；成人潜在自身免疫性糖尿病（LADA）；格雷夫斯氏病；自身免疫性胃炎（AIG）；thyrogastric疾病;自身免疫性多腺综合征（APS） 3型。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Internal Medicine 医学-医学：内科

CiteScore

1.90

自引率

8.30%

发文量

审稿时长

2.2 months

期刊介绍： Internal Medicine is an open-access online only journal published monthly by the Japanese Society of Internal Medicine. Articles must be prepared in accordance with "The Uniform Requirements for Manuscripts Submitted to Biomedical Journals (see Annals of Internal Medicine 108: 258-265, 1988), must be contributed solely to the Internal Medicine, and become the property of the Japanese Society of Internal Medicine. Statements contained therein are the responsibility of the author(s). The Society reserves copyright and renewal on all published material and such material may not be reproduced in any form without the written permission of the Society.