Detection of Four Cases of Familial Hypercholesterolemia during a Workers' Compensation Insurance Secondary Health Examination.

IF 1.1 4区 医学 Q3 MEDICINE, GENERAL & INTERNAL
Internal Medicine Pub Date : 2025-09-01 Epub Date: 2025-05-21 DOI:10.2169/internalmedicine.4790-24
Takayuki Yamaji, Aya Mizobuchi, Yukihito Higashi
{"title":"Detection of Four Cases of Familial Hypercholesterolemia during a Workers' Compensation Insurance Secondary Health Examination.","authors":"Takayuki Yamaji, Aya Mizobuchi, Yukihito Higashi","doi":"10.2169/internalmedicine.4790-24","DOIUrl":null,"url":null,"abstract":"<p><p>Familial hypercholesterolemia (FH), a genetic disorder characterized by the early onset of coronary artery disease, is found in one of 300 people. In the 2022 Japanese FH guidelines, a cut-off value for Achilles tendon thickness measured using ultrasound has been added, enabling the diagnosis of FH during a Workers' Compensation Insurance Secondary Health Examination. In individuals for whom the possibility of FH could not be ruled out based on low-density lipoprotein cholesterol levels, we measured the Achilles tendon thickness by ultrasound and found four cases of FH. The detection of FH in asymptomatic workers is crucial for long-term cardiovascular risk management.</p>","PeriodicalId":13719,"journal":{"name":"Internal Medicine","volume":" ","pages":"2610-2614"},"PeriodicalIF":1.1000,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12463420/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Internal Medicine","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.2169/internalmedicine.4790-24","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/5/21 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
引用次数: 0

Abstract

Familial hypercholesterolemia (FH), a genetic disorder characterized by the early onset of coronary artery disease, is found in one of 300 people. In the 2022 Japanese FH guidelines, a cut-off value for Achilles tendon thickness measured using ultrasound has been added, enabling the diagnosis of FH during a Workers' Compensation Insurance Secondary Health Examination. In individuals for whom the possibility of FH could not be ruled out based on low-density lipoprotein cholesterol levels, we measured the Achilles tendon thickness by ultrasound and found four cases of FH. The detection of FH in asymptomatic workers is crucial for long-term cardiovascular risk management.

工伤保险二次体检中家族性高胆固醇血症4例的检测。
家族性高胆固醇血症(FH)是一种以冠状动脉疾病早发为特征的遗传性疾病,每300人中就有一人患有此病。在2022年日本FH指南中,增加了使用超声测量跟腱厚度的临界值,以便在工人赔偿保险二级健康检查期间诊断FH。在低密度脂蛋白胆固醇水平不能排除FH可能性的个体中,我们通过超声测量跟腱厚度,发现了4例FH。在无症状工人中检测FH对长期心血管风险管理至关重要。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
Internal Medicine
Internal Medicine 医学-医学:内科
CiteScore
1.90
自引率
8.30%
发文量
0
审稿时长
2.2 months
期刊介绍: Internal Medicine is an open-access online only journal published monthly by the Japanese Society of Internal Medicine. Articles must be prepared in accordance with "The Uniform Requirements for Manuscripts Submitted to Biomedical Journals (see Annals of Internal Medicine 108: 258-265, 1988), must be contributed solely to the Internal Medicine, and become the property of the Japanese Society of Internal Medicine. Statements contained therein are the responsibility of the author(s). The Society reserves copyright and renewal on all published material and such material may not be reproduced in any form without the written permission of the Society.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信