Evaluation of the Therapeutic Efficacy of Moist Wound Healing After Fractional CO2 Laser Surgery

IF 2.3 4区 医学 Q2 DERMATOLOGY
Qingmei Jin, Richeng Dong, Jiahui Zhi, Huimin Yin, Meilan Nan, Zhehu Jin, Chenglong Jin
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Abstract

Background

With the popularization of laser therapy, an increasing number of patients are undergoing fractional CO2 laser therapy. It is particularly important to exercise caution and accelerate wound healing after laser surgery.

Aims

This study aimed to examine the clinical efficacy of moist wound healing after fractional CO2 laser therapy.

Patients/Methods

A total of 15 individuals volunteered to undergo fractional CO2 laser therapy. The facial skin was irradiated with a fractional CO2 laser in the deep mode, with an energy of 15 mJ/cm2 and a density of 5%. The left and right sides of the faces were considered the observation and control groups, respectively. After laser therapy, medical cold compress patches were applied on the skin in the control group once a day for approximately 10–15 min, whereas erythromycin ophthalmic ointment was applied on the skin in the observation group 6 times daily for wound care. The wound healing time, duration of erythema, and occurrence of adverse reactions were monitored in both groups.

Results

The observation and control groups received different nursing interventions. The time to regression of erythema and swelling was significantly shorter in the observation group than in the control group. In addition, the scab formed at the wound site was thinner, and shedding was faster in the observation group than in the control group. The Clinical Erythema Assessment score of the observation group was significantly lower than that of the control group (p < 0.05). The wound healing time was 5.73 ± 0.70 days in the observation group and 7.73 ± 0.72 days in the control group, with the difference being statistically significant (p < 0.05). After 30 min and 12 h of nursing intervention, the Visual Analog Scale score of the observation group was significantly lower than that of the control group (p < 0.05). However, after 24 h of treatment, neither group showed significant pain. Both groups showed varying degrees of acne, pustules, and exudation, which subsided within 7 days. Furthermore, the control group had 2 cases of mild pigmentation, which resolved within 3 months. Neither group experienced adverse reactions such as skin infection, depigmentation, or scar formation.

Conclusion

Moist healing therapy can accelerate wound healing and reduce the duration of erythema and edema after fractional CO2 laser therapy, demonstrating potential clinical application value.

Abstract Image

部分CO2激光术后湿性创面愈合疗效评价
背景随着激光治疗的普及,越来越多的患者接受分次CO2激光治疗。尤其重要的是要谨慎行事,加速激光手术后的伤口愈合。目的探讨CO2分次激光治疗湿润创面后的临床疗效。患者/方法共有15人自愿接受部分CO2激光治疗。面部皮肤用深度模式的分数CO2激光照射,能量为15 mJ/cm2,密度为5%。左边和右边的脸分别被认为是观察组和对照组。激光治疗后,对照组皮肤敷医用冷敷贴片1次/ d,持续约10-15 min;观察组皮肤敷红霉素眼药膏6次/ d,进行创面护理。观察两组患者创面愈合时间、红斑持续时间及不良反应发生情况。结果观察组和对照组采用不同的护理干预措施。观察组红斑、肿胀消退时间明显短于对照组。观察组创面处结痂较对照组更薄,脱落速度更快。观察组患者临床红斑评估评分显著低于对照组(p < 0.05)。观察组创面愈合时间为5.73±0.70 d,对照组为7.73±0.72 d,差异有统计学意义(p < 0.05)。护理干预30 min和12 h后,观察组患者的视觉模拟量表评分显著低于对照组(p < 0.05)。然而,治疗24 h后,两组均未出现明显疼痛。两组患者均出现不同程度的痤疮、脓疱、渗出,7 d内消退。对照组轻度色素沉着2例,均在3个月内消退。两组均未出现皮肤感染、色素脱失或瘢痕形成等不良反应。结论湿润愈合治疗可加速CO2分次激光治疗后创面愈合,缩短红斑水肿持续时间,具有潜在的临床应用价值。
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来源期刊
CiteScore
4.30
自引率
13.00%
发文量
818
审稿时长
>12 weeks
期刊介绍: The Journal of Cosmetic Dermatology publishes high quality, peer-reviewed articles on all aspects of cosmetic dermatology with the aim to foster the highest standards of patient care in cosmetic dermatology. Published quarterly, the Journal of Cosmetic Dermatology facilitates continuing professional development and provides a forum for the exchange of scientific research and innovative techniques. The scope of coverage includes, but will not be limited to: healthy skin; skin maintenance; ageing skin; photodamage and photoprotection; rejuvenation; biochemistry, endocrinology and neuroimmunology of healthy skin; imaging; skin measurement; quality of life; skin types; sensitive skin; rosacea and acne; sebum; sweat; fat; phlebology; hair conservation, restoration and removal; nails and nail surgery; pigment; psychological and medicolegal issues; retinoids; cosmetic chemistry; dermopharmacy; cosmeceuticals; toiletries; striae; cellulite; cosmetic dermatological surgery; blepharoplasty; liposuction; surgical complications; botulinum; fillers, peels and dermabrasion; local and tumescent anaesthesia; electrosurgery; lasers, including laser physics, laser research and safety, vascular lasers, pigment lasers, hair removal lasers, tattoo removal lasers, resurfacing lasers, dermal remodelling lasers and laser complications.
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