Developing mRNA Nanomedicines with Advanced Targeting Functions

IF 26.6 1区材料科学 Q1 Engineering

Nano-Micro Letters Pub Date : 2025-02-21 DOI:10.1007/s40820-025-01665-9

Ji Wang, Lijun Cai, Ning Li, Zhiqiang Luo, Haozhen Ren, Bing Zhang, Yuanjin Zhao

引用次数: 0

Abstract

Highlights

The structure and modification strategies of messenger RNA (mRNA), along with advanced delivery carriers, are thoroughly reviewed to showcase their role in targeted drug delivery.
Recent advancements in mRNA nanomedicines, focusing on targeted strategies for various organs, are summarized to illustrate their therapeutic potential.
The major challenges and future perspectives for the clinical translation of targeted mRNA nanomedicines are discussed, emphasizing solutions to biological barriers.

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来源期刊

Nano-Micro Letters NANOSCIENCE & NANOTECHNOLOGY-MATERIALS SCIENCE, MULTIDISCIPLINARY

CiteScore

32.60

自引率

4.90%

发文量

981

审稿时长

1.1 months

期刊介绍： Nano-Micro Letters is a peer-reviewed, international, interdisciplinary, and open-access journal published under the SpringerOpen brand. Nano-Micro Letters focuses on the science, experiments, engineering, technologies, and applications of nano- or microscale structures and systems in various fields such as physics, chemistry, biology, material science, and pharmacy.It also explores the expanding interfaces between these fields. Nano-Micro Letters particularly emphasizes the bottom-up approach in the length scale from nano to micro. This approach is crucial for achieving industrial applications in nanotechnology, as it involves the assembly, modification, and control of nanostructures on a microscale.