Cannabis and mental health in adolescents: changes in associations over 15 years.

IF 3.6 2区医学 Q1 PSYCHIATRY

Social Psychiatry and Psychiatric Epidemiology Pub Date : 2025-02-18 DOI:10.1007/s00127-025-02859-7

R Valter, O Le Nezet, I Obradovic, S Spilka, B Falissard, L Josseran, S Gautier, G Airagnes

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引用次数: 0

Abstract

Purpose: Recent changes in the cannabis market, including decreased adolescence usage, increased Δ9-tetrahydrocannabinol levels and rising mental disorders over the last decade raises questions about the changing profile of cannabis consumers.

Methods: This study explores the trends of associations between regular cannabis use and mental health in five waves of a national representative survey of 17-year-old French adolescents, including more than 150,000 participants. Multivariable models, adjusted for gender and socioeconomic variables, were used.

Results: Cannabis use and mental health indicators showed some variations over time, with increasing divergence between 2017 and 2022. Regular use of cannabis decreased from 7.4% in 2008 to 3.8% in 2022 (p < 0.001). In contrast, suicidal ideation in the past year increased from 16% in 2008 to 18% in 2022 (p = 0.009), although it followed a U-shaped trend. The association between regular cannabis use and suicidal ideation in the past year increased from 1.44 (CI: 1.29-1.61) in 2008 to 2.52 (CI: 2.05-3.10) in 2022. Similarly, the association between cannabis use and antidepressant use in the past year increased from 2.57 (CI: 2.18-3.03) in 2008 to 4.47 (CI: 3.35-5.97) in 2022.

Conclusion: These results suggest that cannabis users are now more prone to mental health disorders compared to 15 years ago. Several mechanisms might explain these findings, including the self-selection of a population with both vulnerabilities, changes in the effects of cannabis, or the use of cannabis as a self-medication strategy.

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大麻与青少年心理健康：15年来关系的变化。

目的：大麻市场最近的变化，包括青少年使用量的减少、Δ9-tetrahydrocannabinol水平的增加以及过去十年中精神障碍的增加，引发了人们对大麻消费者状况变化的质疑。方法：本研究在对17岁的法国青少年进行的全国代表性调查的五次浪潮中探讨了经常使用大麻与心理健康之间的关系趋势，其中包括15万多名参与者。采用多变量模型，对性别和社会经济变量进行调整。结果：大麻使用和心理健康指标随着时间的推移出现了一些变化，2017年至2022年之间的差异越来越大。经常使用大麻的比例从2008年的7.4%下降到2022年的3.8% (p结论：这些结果表明，与15年前相比，大麻使用者现在更容易出现精神健康障碍。有几种机制可以解释这些发现，包括对脆弱人群的自我选择，大麻影响的变化，或将大麻用作自我药物治疗策略。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Social Psychiatry and Psychiatric Epidemiology 医学-精神病学

CiteScore

8.50

自引率

2.30%

发文量

184

审稿时长

3-6 weeks

期刊介绍： Social Psychiatry and Psychiatric Epidemiology is intended to provide a medium for the prompt publication of scientific contributions concerned with all aspects of the epidemiology of psychiatric disorders - social, biological and genetic. In addition, the journal has a particular focus on the effects of social conditions upon behaviour and the relationship between psychiatric disorders and the social environment. Contributions may be of a clinical nature provided they relate to social issues, or they may deal with specialised investigations in the fields of social psychology, sociology, anthropology, epidemiology, health service research, health economies or public mental health. We will publish papers on cross-cultural and trans-cultural themes. We do not publish case studies or small case series. While we will publish studies of reliability and validity of new instruments of interest to our readership, we will not publish articles reporting on the performance of established instruments in translation. Both original work and review articles may be submitted.