Multilayered numerical modelling of bio-thermal aspects during laser assisted treatment of internal haemorrhoid developed in rectum.

IF 2.1 4区 医学 Q3 ENGINEERING, BIOMEDICAL
Jaideep Dutta
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引用次数: 0

Abstract

Haemorrhoids are swollen blood vessels developed around the anus. Internal haemorrhoids are generally not visible from outside due to its growth inside the rectum and it is generally considered as painless. However, a prolapsed internal haemorrhoid may cause discomfort, pain and irritation. For the treatment of internal haemorrhoid, laser assisted therapy would be helpful due to its rooted advantages such as post-surgery minimal pain, lesser bleeding, quicker healing, shorter recovery period, shorter surgical and overall treatment duration, lower risk of recurrence and least risk of post-surgical infections. The genesis of present research work deals with the development of mathematical modelling to capture the bio-thermal response during laser assisted therapy of internal haemorrhoid developed in the rectum. The explicit form of finite difference method is employed as numerical tool for the mathematical study and the physical domain is considered as multilayered tissue (three different layers of rectum: muscle, submucosa and mucosa). A Gaussian laser beam is considered as heat source to destroy the abnormal growth inside the rectum. Temperature variation in multi-layered tissue is investigated for laser heat input and absorption radius along the temporal and spatial coordinate. Temperature drop has been evidenced in the interfaces of multi-layered rectum tissue. The research outcome is verified with the published numerical model with negligible variation.

激光辅助治疗直肠内痔过程中生物热方面的多层数值模拟。
痔疮是在肛门周围形成的肿胀血管。由于内痔生长在直肠内,通常从外部看不出来,通常被认为是无痛的。然而,内痔脱垂可能会引起不适、疼痛和刺激。对于内痔的治疗,激光辅助治疗具有术后疼痛小、出血少、愈合快、恢复期短、手术时间短、整体治疗时间短、复发风险低、术后感染风险小等优点。本研究工作的起源涉及数学模型的发展,以捕捉激光辅助治疗直肠内痔期间的生物热反应。采用有限差分法的显式形式作为数学研究的数值工具,将物理域视为多层组织(直肠的三个不同层:肌肉、粘膜下层和粘膜)。采用高斯激光束作为热源,破坏直肠内的异常生长。研究了激光热输入和吸收半径在多层组织中的时空变化规律。在直肠多层组织的界面处有明显的温度下降。研究结果与已发表的数值模型进行了验证,变化可以忽略不计。
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来源期刊
Lasers in Medical Science
Lasers in Medical Science 医学-工程:生物医学
CiteScore
4.50
自引率
4.80%
发文量
192
审稿时长
3-8 weeks
期刊介绍: Lasers in Medical Science (LIMS) has established itself as the leading international journal in the rapidly expanding field of medical and dental applications of lasers and light. It provides a forum for the publication of papers on the technical, experimental, and clinical aspects of the use of medical lasers, including lasers in surgery, endoscopy, angioplasty, hyperthermia of tumors, and photodynamic therapy. In addition to medical laser applications, LIMS presents high-quality manuscripts on a wide range of dental topics, including aesthetic dentistry, endodontics, orthodontics, and prosthodontics. The journal publishes articles on the medical and dental applications of novel laser technologies, light delivery systems, sensors to monitor laser effects, basic laser-tissue interactions, and the modeling of laser-tissue interactions. Beyond laser applications, LIMS features articles relating to the use of non-laser light-tissue interactions.
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