Faster recovery in patients with facial nerve palsy treated with contralateral botulinum toxin injection: a case-control study.

IF 1.9 3区医学 Q2 OTORHINOLARYNGOLOGY

European Archives of Oto-Rhino-Laryngology Pub Date : 2025-02-18 DOI:10.1007/s00405-025-09247-6

Jung Mee Park, Ji Hyung Lim, Jae Sang Han, Shi Nae Park

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引用次数: 0

Abstract

Purpose: Botulinum toxin (BTX, Botox) is increasingly used as an adjunct therapy to oral steroids in the management of facial paralysis, with positive outcomes. This study aimed to evaluate the additive effect of BTX injection on the non-paralyzed side and propose optimal injection timing for recovery time.

Methods: A total of 48 atraumatic facial paralysis patients who visited Seoul St. Mary's hospital for facial palsy between June 2015 and May 2021 were retrospectively reviewed. Patients were divided into 2 groups: the BTX injection group (BG) and the non-BTX injection group (NBG). We analyzed the recovery rate of facial palsy to H-B grade II or lower in each group, and conducted telephone surveys to collect subjective satisfaction data after BTX injection.

Results: Days of recovery to H-B grade II from symptom onset were 93.0 ± 62 and 68.7 ± 66.6 in NBG and BG, respectively. Early BTX injection (less than 17.5 days from symptom onset) was a prognostic factor for recovery to H-B grade II in less than 1 month (R² = 0.935, B = 1.738, p < 0.001). Telephone survey showed subjective satisfaction in all aspects 1 month after BTX injection: function (83.3%), cosmetic (70.9%), and recovery (54.2%).

Conclusion: Early contralateral facial BTX injection can shorten the recovery period of atraumatic facial palsy.

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来源期刊

European Archives of Oto-Rhino-Laryngology 医学-耳鼻喉科学

CiteScore

5.30

自引率

7.70%

发文量

537

审稿时长

2-4 weeks

期刊介绍： Official Journal of European Union of Medical Specialists – ORL Section and Board Official Journal of Confederation of European Oto-Rhino-Laryngology Head and Neck Surgery "European Archives of Oto-Rhino-Laryngology" publishes original clinical reports and clinically relevant experimental studies, as well as short communications presenting new results of special interest. With peer review by a respected international editorial board and prompt English-language publication, the journal provides rapid dissemination of information by authors from around the world. This particular feature makes it the journal of choice for readers who want to be informed about the continuing state of the art concerning basic sciences and the diagnosis and management of diseases of the head and neck on an international level. European Archives of Oto-Rhino-Laryngology was founded in 1864 as "Archiv für Ohrenheilkunde" by A. von Tröltsch, A. Politzer and H. Schwartze.