{"title":"Integrating Artificial Intelligence and Digital Innovations in Psychedelic and Brain Therapeutics.","authors":"Robert B Kargbo","doi":"10.1021/acsmedchemlett.5c00029","DOIUrl":null,"url":null,"abstract":"<p><p>The intersection of artificial intelligence (AI), digital therapeutics, and advanced communication frameworks offers transformative opportunities for addressing mental health disorders, neurodegenerative diseases, and communication challenges in modern networks. This Patent Highlight examines three pivotal patents that introduce deuterated empathogens for safer psychiatric treatments, AI-powered digital platforms for cognitive and immune function enhancement, and robust frameworks for AI/ML performance monitoring in wireless systems. Together, these innovations represent a paradigm shift in therapeutic and technological approaches, emphasizing the synergy of molecular and digital advancements in tackling global health and communication challenges.</p>","PeriodicalId":20,"journal":{"name":"ACS Medicinal Chemistry Letters","volume":"16 2","pages":"213-215"},"PeriodicalIF":3.5000,"publicationDate":"2025-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11831375/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"ACS Medicinal Chemistry Letters","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1021/acsmedchemlett.5c00029","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/2/13 0:00:00","PubModel":"eCollection","JCR":"Q2","JCRName":"CHEMISTRY, MEDICINAL","Score":null,"Total":0}
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Abstract
The intersection of artificial intelligence (AI), digital therapeutics, and advanced communication frameworks offers transformative opportunities for addressing mental health disorders, neurodegenerative diseases, and communication challenges in modern networks. This Patent Highlight examines three pivotal patents that introduce deuterated empathogens for safer psychiatric treatments, AI-powered digital platforms for cognitive and immune function enhancement, and robust frameworks for AI/ML performance monitoring in wireless systems. Together, these innovations represent a paradigm shift in therapeutic and technological approaches, emphasizing the synergy of molecular and digital advancements in tackling global health and communication challenges.
期刊介绍：
ACS Medicinal Chemistry Letters is interested in receiving manuscripts that discuss various aspects of medicinal chemistry. The journal will publish studies that pertain to a broad range of subject matter, including compound design and optimization, biological evaluation, drug delivery, imaging agents, and pharmacology of both small and large bioactive molecules. Specific areas include but are not limited to:
Identification, synthesis, and optimization of lead biologically active molecules and drugs (small molecules and biologics)
Biological characterization of new molecular entities in the context of drug discovery
Computational, cheminformatics, and structural studies for the identification or SAR analysis of bioactive molecules, ligands and their targets, etc.
Novel and improved methodologies, including radiation biochemistry, with broad application to medicinal chemistry
Discovery technologies for biologically active molecules from both synthetic and natural (plant and other) sources
Pharmacokinetic/pharmacodynamic studies that address mechanisms underlying drug disposition and response
Pharmacogenetic and pharmacogenomic studies used to enhance drug design and the translation of medicinal chemistry into the clinic
Mechanistic drug metabolism and regulation of metabolic enzyme gene expression
Chemistry patents relevant to the medicinal chemistry field.
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