Cover Picture: Enhancing electrochemical xanthine detection: a two-step incubation strategy to minimize interference from ascorbic acid (BKCS 2/2025) Taeyeon Yoo, Seonhwa Park, Hyoeun Lee, Subin Park, Youngsuk Kim, Haesik Yang

Abstract

This cover image illustrates the selective electrochemical detection of xanthine in serum with interfering species such as ascorbic acid and uric acid. It features crystals formed in the fingers by gout, depicted with glitter effects to enhance their visual impact. The image also demonstrates the electron transfer from xanthine to an electrode, facilitated by Os(bpy)2Cl2+ and xanthine dehydrogenase. This research contributes to the early diagnosis of purine-related metabolic disorders. More details are available in the article by Taeyeon Yoo, Seonhwa Park, Hyoeun Lee, Subin Park, Youngsuk Kim, Haesik Yang