Runyou Ye, Jialin Ming, Qinyue Tao, Tian-Yu Gao, Jian-Heng Ye, Da-Gang Yu, Xiangge Zhou
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引用次数: 0
Abstract
Isofunctional reactions involving the cleavage of carbon-carbon double bonds (C=C) hold an important position in organic synthesis, as they allow for the restructuring of alkene carbon chains and enable the exchange of functional groups without introducing exogenous groups. Currently, these reactions are primarily divided into C=C/C=C metathesis and C=C/C=O metathesis, with most relying on the use of transition metal catalysts. We report herein a C=C/CH2 metathesis reaction that obviates the need for transition metals and directing groups, and is characterized by economic and straightforward operation. This reaction not only facilitates the replacement of nitriles with ketones, but also enables the replacement of ketones with nitriles, demonstrating great universality.
期刊介绍：
Science China Chemistry, co-sponsored by the Chinese Academy of Sciences and the National Natural Science Foundation of China and published by Science China Press, publishes high-quality original research in both basic and applied chemistry. Indexed by Science Citation Index, it is a premier academic journal in the field.
Categories of articles include:
Highlights. Brief summaries and scholarly comments on recent research achievements in any field of chemistry.
Perspectives. Concise reports on thelatest chemistry trends of interest to scientists worldwide, including discussions of research breakthroughs and interpretations of important science and funding policies.
Reviews. In-depth summaries of representative results and achievements of the past 5–10 years in selected topics based on or closely related to the research expertise of the authors, providing a thorough assessment of the significance, current status, and future research directions of the field.
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