Epidemic status of echinococcosis, brucellosis, and tuberculosis among rural residents in three counties of Wuzhong City, Ningxia, China in 2023

IF 2 Q3 INFECTIOUS DISEASES
Yan Huo , Jing Tang , MiXue Guo , SiYu Hou , Wei Zhao
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Abstract

In recent years, the rapid development of animal husbandry in rural China has brought about the problem of zoonosis. In 2023, a cross-sectional study was carried out to gain an in-depth understanding of the infection status and influencing factors of three common zoonoses (echinococcosis, brucellosis and tuberculosis) among rural residents in three counties/districts of Wuzhong City, Ningxia. For the selection of the study participants, a cluster sampling approach was adopted. We recruited permanent rural residents from the three counties, without imposing any age limitations, to ensure a broad and representative sample. A field survey was then meticulously carried out among these individuals, and blood samples were collected simultaneously. The collected blood was processed to obtain serum, which was subsequently utilized to detect pathogen-specific IgG antibodies using the Enzyme-Linked Immunosorbent Assay (ELISA). Through a comprehensive questionnaire survey administered to the same group of participants, a detailed analysis was performed to assess the current situation of the infections and to identify the various factors that might be influencing the occurrence and spread of these diseases within this specific population. A total of 1847 people participated in the survey, with their ages ranging from 8 to 94 years old. Subsequently, the corresponding blood samples were tested strictly in accordance with the number of valid questionnaires. The detection rates for these diseases were 4.93 % (91/1844) for echinococcosis, 20.52 % (378/1842) for brucellosis, and 7.26 % (134/1847) for tuberculosis. Univariate analysis revealed no significant variation in the positive detection rate of echinococcosis across different demographic groups. However, factors such as sex, age, educational level, occupation, living environment, and breeding conditions and slaughtering situation significantly influenced the positive detection rate of serum antibodies against brucellosis (P < 0.05). The positive rate of serum antibodies for tuberculosis varied under different breeding and protection conditions (P < 0.05). Multivariate analysis identified risk factors for brucellosis, including male (OR = 1.944, P < 0.001), living with a large number of sheep (OR = 1.640, P = 0.001), and home slaughter (OR = 1.427, P = 0.007), while non-agricultural workers were found to be protective (OR = 0.493, P = 0.003). For tuberculosis, risk factors included raising cattle and sheep at home (OR = 1.877, P = 0.002) and lacking protective contact with these animals (OR = 2.138, P = 0.001). To achieve effective and precise prevention and control of zoonoses, comprehensive measures should be implemented.
2023年宁夏吴中市3县农村居民棘球蚴病、布鲁氏菌病和结核病流行状况
近年来,中国农村畜牧业的快速发展带来了人畜共患病问题。2023年,为深入了解宁夏吴中市3个县(区)农村居民棘球蚴病、布鲁氏菌病和结核病3种常见人畜共患病的感染现状及影响因素,开展了横断面研究。对于研究对象的选择,采用整群抽样的方法。我们从三个县抽取农村常住人口,不设年龄限制,保证样本的广泛性和代表性。然后对这些人进行了细致的实地调查,同时收集了血液样本。采集的血液经过处理获得血清,随后使用酶联免疫吸附试验(ELISA)检测病原体特异性IgG抗体。通过对同一组参与者进行全面的问卷调查,进行了详细的分析,以评估感染的现状,并确定可能影响这些疾病在这一特定人群中发生和传播的各种因素。共有1847人参与了调查,他们的年龄从8岁到94岁不等。随后,严格按照有效问卷的数量对相应的血液样本进行检测。棘球蚴病检出率为4.93%(91/1844),布鲁氏菌病检出率为20.52%(378/1842),结核病检出率为7.26%(134/1847)。单因素分析显示不同人群棘球蚴病阳性检出率无显著差异。而性别、年龄、文化程度、职业、生活环境、养殖条件和屠宰情况等因素对布鲁氏菌病血清抗体阳性率有显著影响(P <;0.05)。在不同的饲养和保护条件下,血清结核抗体阳性率存在差异(P <;0.05)。多因素分析确定了布鲁氏菌病的危险因素,包括男性(OR = 1.944, P <;与大量绵羊一起生活(OR = 1.640, P = 0.001)和家庭屠宰(OR = 1.427, P = 0.007),而非农业工人被发现具有保护作用(OR = 0.493, P = 0.003)。结核病的危险因素包括家中饲养牛羊(OR = 1.877, P = 0.002)和缺乏与这些动物的保护性接触(OR = 2.138, P = 0.001)。实现人畜共患病有效精准防控,需要综合施策。
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来源期刊
Parasite Epidemiology and Control
Parasite Epidemiology and Control Medicine-Infectious Diseases
CiteScore
5.70
自引率
3.10%
发文量
44
审稿时长
17 weeks
期刊介绍: Parasite Epidemiology and Control is an Open Access journal. There is an increasing amount of research in the parasitology area that analyses the patterns, causes, and effects of health and disease conditions in defined populations. This epidemiology of parasite infectious diseases is predominantly studied in human populations but also spans other major hosts of parasitic infections and as such this journal will have a broad remit. We will focus on the major areas of epidemiological study including disease etiology, disease surveillance, drug resistance and geographical spread and screening, biomonitoring, and comparisons of treatment effects in clinical trials for both human and other animals. We will also look at the epidemiology and control of vector insects. The journal will also cover the use of geographic information systems (Epi-GIS) for epidemiological surveillance which is a rapidly growing area of research in infectious diseases. Molecular epidemiological approaches are also particularly encouraged.
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