Does the interval between the first unprovoked seizure and EEG influence the diagnostic yield?

IF 2.3 3区医学 Q2 BEHAVIORAL SCIENCES

Epilepsy & Behavior Pub Date : 2025-02-20 DOI:10.1016/j.yebeh.2025.110311

Vaidehi Naganur , Jacqueline Tse , Jayan Muthusamy , Shakira Snell , Shuyu Wang , Udaya Seneviratne

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引用次数: 0

Abstract

Objective

There is no consensus on the optimum time for an EEG after the first seizure. We sought to investigate whether the timing of an EEG after a first unprovoked seizure influences its diagnostic yield.

Methods

A retrospective analysis was conducted at a tertiary hospital in Australia. Adult patients who presented with a first unprovoked seizure were studied. Using multivariable logistic regression, we investigated the association of EEG timing, seizure presentation, and risk factors for epilepsy with the presence of interictal epileptiform discharges (IED) in the EEG as the outcome. The chi-square test compared EEG yields across each week after the seizure.

Results

Among 452 patients, the time from seizure to EEG did not show a statistically significant impact on the presence of IEDs (OR = 1, 95 % CI 0.99–1, p = 0.095). The yield of epileptiform abnormalities generally declined over time but was not statistically significant across weeks (p = 0.40). A modest but significant relationship was found between age and the likelihood of detecting IEDs, with older age associated with a lower yield of abnormalities (OR = 0.98, 95 % CI 0.973–0.997, p = 0.016).

Conclusion

Our results suggest that the timing of the EEG following the first unprovoked seizure does not significantly impact the diagnostic yield.

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来源期刊

Epilepsy & Behavior 医学-行为科学

CiteScore

5.40

自引率

15.40%

发文量

385

审稿时长

43 days

期刊介绍： Epilepsy & Behavior is the fastest-growing international journal uniquely devoted to the rapid dissemination of the most current information available on the behavioral aspects of seizures and epilepsy. Epilepsy & Behavior presents original peer-reviewed articles based on laboratory and clinical research. Topics are drawn from a variety of fields, including clinical neurology, neurosurgery, neuropsychiatry, neuropsychology, neurophysiology, neuropharmacology, and neuroimaging. From September 2012 Epilepsy & Behavior stopped accepting Case Reports for publication in the journal. From this date authors who submit to Epilepsy & Behavior will be offered a transfer or asked to resubmit their Case Reports to its new sister journal, Epilepsy & Behavior Case Reports.