Andre Jin Wei Loh, Ee Lynn Ting, Yu Heng Kwan, Ting Hui Woon, Jie Kie Phang, Chin Teck Ng, Warren Fong
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引用次数: 0
Abstract
Introduction: Studies have shown that patients with rheumatoid arthritis (RA) have lower levels of physical activity (PA) than healthy controls, despite the benefits of PA in reducing pain and stiffness. We aimed to compare the levels of PA in patients with RA with that of the general population and identify factors associated with meeting the World Health Organization (WHO) recommendations for PA.
Methods: Consecutive patients with RA were recruited from an outpatient rheumatology clinic in a tertiary hospital in Singapore. Data for the general population were obtained from the Singapore Health 2012 study. To obtain comparable controls from the general population, we performed propensity score matching based on age and gender.
Results: Sixty patients with RA were recruited. The proportions of patients with RA and controls who met WHO recommendations for PA were similar (78.3% vs. 80.0%, P = 0.82). After propensity matching, patients with RA spent significantly less time on work-related PA compared to controls (54.3 ± 147.4 min vs. 73.0 ± 132.6 min, P < 0.01). Disease activity was insignificant in determining whether WHO recommendations for PA were met in patients with RA. In the multivariable logistic regression, being employed (odds ratio 4.72, 95% confidence interval 1.20-18.59) was associated with meeting WHO recommendations.
Conclusions: In this study, the proportion of patients with RA who met the recommendations for PA was similar to that of controls after propensity score matching. Among patients with RA, being employed was associated with meeting WHO recommendations for PA.
研究表明,类风湿性关节炎(RA)患者的身体活动(PA)水平低于健康对照组,尽管PA在减轻疼痛和僵硬方面有好处。我们的目的是比较RA患者的PA水平与一般人群的PA水平,并确定符合世界卫生组织(WHO)推荐的PA水平的相关因素。方法:从新加坡一家三级医院的风湿病门诊连续招募RA患者。一般人群的数据来自2012年新加坡健康研究。为了从一般人群中获得可比较的对照,我们根据年龄和性别进行了倾向评分匹配。结果:60例RA患者入选。RA患者和对照组符合who推荐的PA的比例相似(78.3%对80.0%,P = 0.82)。倾向匹配后,RA患者在工作相关PA上花费的时间明显少于对照组(54.3±147.4 min vs. 73.0±132.6 min, P < 0.01)。疾病活动度对于确定WHO推荐的RA患者PA是否满足没有意义。在多变量logistic回归中,被雇用(优势比4.72,95%置信区间1.20-18.59)与符合世卫组织建议相关。结论:在本研究中,经过倾向评分匹配后,符合推荐PA的RA患者比例与对照组相似。在类风湿性关节炎患者中,受雇与WHO推荐的PA相关。