Relevance of ecological momentary assessment for medication adherence in clinical settings: A precision psychiatry approach

IF 3.1 3区 心理学 Q1 PSYCHOLOGY, CLINICAL
Valentine Chirokoff, Arnaud Tessier, Fuschia Serre, Maud Dupuy, Marc Auriacombe, Sandra Chanraud, Sylvie Berthoz, Melina Fatseas, David Misdrahi
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引用次数: 0

Abstract

Background

Medication non-adherence is a leading cause of treatment failure in psychiatric populations. However, current studies highlight the lack of methodological guidance on medication assessments. Ecological Momentary Assessment (EMA), using smartphone-based evaluations, shows promise for real-time monitoring in everyday settings.

Aims

This study evaluated EMA's effectiveness in assessing medication adherence in patients with schizophrenia, depression, and substance use disorders (SUD), covering various treatment regimens.

Materials & Methods

A total of 133 participants (27 with schizophrenia, 20 with depression, 44 with SUDs, and 42 healthy controls) completed EMA via study-provided smartphones five times daily over 1 week. Treatment regimens, categorized by mono vs. polytherapy and single vs. multiple daily doses, were documented. EMA adherence was calculated from the completion rate of the assessments, while medication adherence was assessed daily for patients. Both mean medication adherence and adherence variation over time were analysed by diagnosis and treatment regimen.

Results

All groups demonstrated high mean EMA and medication adherence, with minor variations across treatment types. Importantly, patients showed improved adherence over time, independently of diagnosis or regimen.

Discussion

These findings indicate EMA's potential as an effective method for capturing medication adherence in psychiatric populations.

Conclusion

The approach's capacity for real-time, context-sensitive data collection could reveal adherence patterns and changes not detectable by conventional methods, offering valuable insights for clinical practice.

Abstract Image

Abstract Image

临床环境中对药物依从性的生态瞬时评估的相关性:一种精确的精神病学方法。
背景:药物不依从性是精神科人群治疗失败的主要原因。然而,目前的研究强调缺乏药物评估的方法学指导。生态瞬间评估(EMA)使用智能手机进行评估,有望在日常环境中进行实时监测。目的:本研究评估了EMA在评估精神分裂症、抑郁症和物质使用障碍(SUD)患者药物依从性方面的有效性,涵盖了各种治疗方案。材料与方法:共有133名参与者(27名精神分裂症患者,20名抑郁症患者,44名sud患者和42名健康对照者)通过研究提供的智能手机完成EMA,每天5次,持续1周。治疗方案分为单药与多药、单药与多药。EMA依从性是根据评估的完成率计算的,而药物依从性是每天对患者进行评估的。通过诊断和治疗方案分析平均药物依从性和依从性随时间的变化。结果:所有组均表现出较高的平均EMA和药物依从性,不同治疗类型差异较小。重要的是,随着时间的推移,患者表现出更好的依从性,独立于诊断或治疗方案。讨论:这些发现表明EMA作为捕获精神科人群药物依从性的有效方法的潜力。结论:该方法具有实时、上下文敏感的数据收集能力,可以揭示常规方法无法检测到的依从性模式和变化,为临床实践提供有价值的见解。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
5.80
自引率
3.20%
发文量
57
期刊介绍: The British Journal of Clinical Psychology publishes original research, both empirical and theoretical, on all aspects of clinical psychology: - clinical and abnormal psychology featuring descriptive or experimental studies - aetiology, assessment and treatment of the whole range of psychological disorders irrespective of age group and setting - biological influences on individual behaviour - studies of psychological interventions and treatment on individuals, dyads, families and groups
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